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ProteomicsIdentifying Compartment-specific Alloimmune Targets After Renal Transplantation by integrated genomics
Microarray technology has evolved as a powerful tool over the last decade, to identify biomarkers and study the mechanisms of diseases. We propose a novel application of integrated genomics by combining transcriptional levels with serological antibody profiling after kidney transplantation, with the...
ORGANISM(S): Homo sapiens 
2010-05-26 | E-GEOD-10452 | biostudies-arrayexpress
TranscriptomicsLocal regulation and clinical impact of complement gene expression in deceased and living donor kidney allografts
The biopsy samples obtained at implantation segregated in 2 distinct groups according to donor origin, with a cluster of 319 unique identified genes higher expressed in DD compared to LD kidneys, and 329 genes lower expressed (false discovery rate <5%). Using pathway analysis software a significant ...
ORGANISM(S): Homo sapiens 
2008-04-16 | E-GEOD-11166 | biostudies-arrayexpress
TranscriptomicsIntragraft anti-viral-specific gene expression as a distinctive transcriptional signature for polyomavirus-associated nephropathy
Polyoma virus nephropathy (PVAN) is a common cause of kidney allograft dysfunction and loss. Microscopic descriptions of PVAN are very similar to T-cell mediated rejection (TCMR) and have unclear underlying molecular mechanisms. To identify PVAN-specific gene expression, we analyzed 162 kidney biops...
ORGANISM(S): Homo sapiens 
2016-09-30 | E-GEOD-72925 | biostudies-arrayexpress
TranscriptomicsBIOMARGIN study: Gene expression profiling in patients with a kidney transplantation
Microarrays were used to analyze the gene expression in peripheral blood and kidney allograft biopsies from patients with a kidney transplantation to get more insight in the molecular mechanisms underlying the different clinical phenotypes of kidney transplant rejection. 117 peripheral blood samples...
ORGANISM(S): Homo sapiens 
2019-08-15 | E-GEOD-129166 | biostudies-arrayexpress
UnknownEvaluation of the SARS-CoV-2 positivity ratio and upper respiratory tract viral load among asymptomatic individuals screened before hospitalization or surgery in Flanders, Belgium.
Not available
S-EPMC8584712 | biostudies-literature
ProteomicsA Circulating Antibody Panel for Pre-transplant Prediction of FSGS Recurrence after Kidney Transplantation
Recurrence of focal segmental glomerulosclerosis (rFSGS) after kidney transplantation is a cause of early and accelerated graft loss. Immuneadsorption can alleviate renal dysfunction and suggests that circulating antibodies (Ab) are likely implicated in disease pathogenesis. To evaluate pathogenic A...
ORGANISM(S): Homo sapiens 
2014-11-04 | E-GEOD-57099 | biostudies-arrayexpress
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