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Background: Molecular adaptations in the striatum mediated by dopamine (DA) denervation or Levodopa (L-dopa) treatment have been implicated with the motor deficits found in Parkinsonâ??s disease (PD). Alterations in glutamatergic neurotransmission and anti-oxidant mechanisms are reported to play imp...
ORGANISM(S): Homo sapiens 
Nair2016 - Integration of calcium and dopamine signals by D1R-expressing medium-sized spiny neurons This model is described in the article: Role of DARPP-32 and ARPP-21 in the Emergence of Temporal Constraints on Striatal Calcium and Dopamine Integration. Nair AG, Bhalla US, H...
2016-09-16 | MODEL1603270000 | BioModels
Background: Molecular adaptations in the striatum mediated by dopamine (DA) denervation or Levodopa (L-dopa) treatment have been implicated with the motor deficits found in Parkinson’s disease (PD). Alterations in glutamatergic neurotransmission and anti-oxidant mechanisms are reported to play imp...
ORGANISM(S): Homo sapiens 
Characterization of Glutathione S-transferase activity associated with phase II drug metabolism.
ORGANISM(S): Mus musculus (Mouse) 
2018-10-22 | PXD006920 | Pride
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