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TranscriptomicsRecruitment of GSH into the nucleus during cell proliferation
The essential thiol antioxidant, glutathione (GSH) is recruited into the nucleus of mammalian cells early in cell proliferation, suggesting a key role of the nuclear thiol pool in cell cycle regulation. However, the functions of nuclear GSH (GSHn) and its integration with the cytoplasmic GSH (GSHc) ...
ORGANISM(S): Arabidopsis thaliana 
2010-02-27 | E-GEOD-20454 | biostudies-arrayexpress
GenomicsFervidobacterium pennivorans strain:GSH
Fervidobacterium pennivorans strain:GSH Genome sequencing
PRJNA979142 | ENA
TranscriptomicsDiethyl maleate inhibits MCA+TPA transformed cell growth via modulation of GSH, MAPK, and cancer pathways
Murine or human cancer cells have high glutathione levels. Depletion of the elevated GSH inhibits proliferation of cancer cells. Molecular basis for this observation is little understood. In an attempt to find out the underlying mechanism, we reproduced these effects in transformed C3H10T1/2 and BAL...
ORGANISM(S): Mus musculus 
2014-06-02 | E-GEOD-44650 | biostudies-arrayexpress
TranscriptomicsEffect of GSH gene expression peofile of Arabidopsis thaliana
GSH, being a versatile molecule, is actively involved in various bilogical processe of plant system. Our previous studies identifies an active role of GSH in plant defense signaling network. Here, we used microarray under GSH treated condition to obtain a global expression profiling under this alter...
ORGANISM(S): Arabidopsis thaliana 
2013-04-02 | E-GEOD-45677 | biostudies-arrayexpress
TranscriptomicsIncreased level of glutathione contributes to stress tolerances and global translational changes in Arabidopsis
Polysomal profiling results showed that global translation was enhanced in roots after 8 h and in shoots after 24 h of GSH treatment. By performing transcriptomic analyses of steady-state and polysome-bound mRNAs in GSH-treated plants, we reveal that GSH has more a greatersubstantial impact on trans...
ORGANISM(S): Arabidopsis thaliana 
2015-03-28 | E-GEOD-67356 | biostudies-arrayexpress
TranscriptomicsArabidopsis GSH GLu AtGLR3.3
Arabidopsis wild type and atglr3.3 mutant seedlings were cultured on 0.7% (w/v) agar medium containing half strength of MS basic salt with 1% sucrose (w/v), 5mM MES, pH 5.7. 10-day-old seedlings were equilibrated in the CK buffer for 24 hours. Then, these seedlings were either treated with the CK bu...
ORGANISM(S): Arabidopsis thaliana 
2013-09-30 | E-MEXP-3885 | biostudies-arrayexpress
GenomicsFervidobacterium pennivorans subsp. shakshaketiis strain:GSH
Fervidobacterium pennivorans subsp. shakshaketiis strain:GSH Genome sequencing
PRJNA814007 | ENA
ProteomicsGlobal and mitochondrial proteomics under GSH depletion
Glutathione (GSH) is a tripeptide thiol abundantly present in all eukaryotes1. As the major site of oxidative metabolism, mitochondria must maintain sufficient levels of GSH in order to perform key protective and biosynthetic functions. GSH is exclusively synthesized in the cytosol, yet how it enter...
ORGANISM(S): Homo sapiens (Human) 
2021-11-15 | PXD027673 | Pride
Lc-ms/ms Tmtpro Gsh Mitochondria 
GenomicsImpaired GSH biosynthesis disrupts eye development and PAX6 function
Impaired GSH biosynthesis disrupts eye development and PAX6 function
PRJNA732284 | ENA
GenomicsTranscriptome profiling of GLUTag cells with NaHS and GSH treatment
Transcriptome profiling of GLUTag cells with NaHS and GSH treatment
PRJNA912111 | ENA
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