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TranscriptomicsTranscription profiling of mouse SKG FR4-CD4+ cells and age-matched BALB/c FR4-CD4+ cells, and between IFN-g-/- CD4+ cells transferred to RAG2-/- mice and IL-6-/- CD4+ T cells transferred to IL-6-/- RAG2-/- mice
Th17 cells are enriched by sorting FR4-CD4+ T cells from SKG mice. A large number of Th17 cells also develop spontaneously when CD4+ T cells from IFN-g-deficient (IFN-g-/-) BALB/c mice are transferred to T cell-deficient RAG2-deficient (RAG2-/-) mice and subjected to homeostatic proliferation, where...
ORGANISM(S): Mus musculus 
2008-06-16 | E-GEOD-9316 | biostudies-arrayexpress
TranscriptomicsDifferential gene expression in GBS6 cells after EWS-POU5F1 knockdown
Our objective is to clarify the function of EWS-POU5F1 chimera. Specifially, GBS6 cells were established from an undifferentiated bone sarcoma carrying translocation t(6;22)(p21;q12). The translocation resulted in a gene fusion between EWS and POU5F1. Gene expression analysis of t(6;22) undifferenti...
ORGANISM(S): Homo sapiens 
2009-05-31 | E-GEOD-12320 | biostudies-arrayexpress
UnknownPrediction of the Sex-Associated Genomic Region in Tunas (Thunnus Fishes).
Not available
S-EPMC8693018 | biostudies-literature
TranscriptomicsMicroarray analysis of gene expression in ATM-deficient MEFs
The expression of interferon-related genes was more enhanced in irradiated ATM-deficient mouse embryonic fibroblasts (MEFs) than in irradiated ATM wild-type MEFs. Nonirradiated-ATM-WT vs Irradiated-ATM-WT vs Nonirradaited-ATM-KO vs IrradiatedATM-KO
ORGANISM(S): Mus musculus 
2012-06-19 | E-GEOD-23116 | biostudies-arrayexpress
TranscriptomicsThe induced APL cells generated by the transplantation of PML-RARA-transduced human CD34+ hematopoietic cells into immunodeficient mice
A humanized in vivo APL model has been established utilizing the retroviral transduction of PML-RARA into human CD34+ hematopoietic cells and the transplantation of these cells into immunodeficient mice. The resultant leukemia recapitulated human APL phenotypically, and was clustered in the same cat...
ORGANISM(S): Homo sapiens 
2014-11-04 | E-GEOD-49344 | biostudies-arrayexpress
UnknownCausal interaction of metabolic oscillations in monolayers of Hela cervical cancer cells: emergence of complex networks.
Not available
S-EPMC11876358 | biostudies-literature
ProteomicsArabidopsis Wdr8 interactors identification
To identify Arabidopsis Wdr8 interactors, immunoprecipitation associated LC-MS/MS analysis was carried out. Crude proteins extracted from Wdr8-GFP expressing transgenic plants was subjected to the immuno-precipitation assay using GFP antibody magnetic beads (µMACS GFP isolation kit, Miltenyi Biotec)...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2022-02-17 | PXD026063 | Pride
Gfp antibody coupled immunoprecipitation Arabidopsis seedlings Lc-ms/ms 
TranscriptomicsExpression data from BCG-immunized monkey PBMCs stimulated with lipid antigen
The role of CD1-restricted, lipid-specific T cells in vivo remains to be elucidated. We used microarrays to detail the global program of gene expression accompanied by the activation of CD1-restricted, lipid-specific T cells. Monkeys were immunized with BCG bacteria to evoke CD1-restricted, mycolyl ...
ORGANISM(S): Macaca mulatta 
2014-03-01 | E-GEOD-44963 | biostudies-arrayexpress
TranscriptomicsMicroarray-based global mapping of integration sites of retrotransposon, intracisternal A-particle, in mouse genome
Mammalian genomes have evolutionary harbored numerous mobile elements, a part of which are still active and evoke genomic instability. Their movement and positional diversity occasionally result in phenotypic changes and variation by causing altered expression and disruption of neighboring genes in...
ORGANISM(S): Mus musculus 
2008-05-03 | E-GEOD-9572 | biostudies-arrayexpress
TranscriptomicsRNAi-mediated knockdown of Xist can rescue the impaired postimplantation development of cloned mouse embryo
Cloning mammals by somatic cell nuclear transfer (SCNT) is highly inefficient. Most SCNT-generated embryos die after implantation because of unidentified, complex epigenetic errors in the process of postimplantation embryonic development. Here, we identified the most upstream level of dysfunction le...
ORGANISM(S): Mus musculus 
2011-11-17 | E-GEOD-33208 | biostudies-arrayexpress
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