Sort   by:  
 Page size 
ProteomicsCysteine excess triggers a mitochondrial iron-dependent cell death
Thiol-containing metabolites are central to cellular redox homeostasis1. Among these, cysteine functions as a proteogenic amino acid, supports redox balance and iron–sulfur cluster biogenesis, and, when depleted, triggers ferroptosis2. Cells nevertheless maintain cysteine at low levels, reflecting i...
ORGANISM(S): Homo sapiens (Human) 
2026-08-14 | PXD082345 | Pride
Cysteine Cell death Iron 
MetabolomicsGNPS - Targeting FSP1 triggers ferroptosis in lung cancer
Raw mass spectrometry data were acquired via LC-MS to quantify oxidized lipids and Coenzyme Q9 (CoQ9) in mouse lung tumor and cell line samples. A Parallel Reaction Monitoring (PRM) strategy was employed for oxidized lipids, while a Data-Dependent Acquisition (DDA) method was used for CoQ9.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2025-08-19 | MSV000098883 | GNPS
ProteomicsA non-canonical vitamin K cycle is a potent ferroptosis suppressor
Raw files corresponding to LC-MS-based relative quantification of oxidized lipids in Pfa1 cells and mouse liver samples subjected to ferroptosis. Data were acquired in parallel reaction monitoring (PRM) MS/MS mode.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2022-05-19 | MSV000089489 | MassIVE
Sort   by:  
 Page size