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UnknownSpatiotemporal ATP Dynamics during AKI Predict Renal Prognosis.

Background

Depletion of ATP in renal tubular cells plays the central role in the pathogenesis of kidney diseases. Nevertheless, inability to visualize spatiotemporal in vivo ATP distribution and dynamics has hindered further analysis.

Methods

A novel mouse line systemically exp...
S-EPMC7790205 | biostudies-literature
UnknownDefective autophagy and AMPK inactivation drive ferroptosis in diabetic kidney disease.

Aims/hypothesis

Ferroptosis, a regulated form of cell death characterised by excessive lipid peroxidation, plays a critical role in acute kidney injury (AKI). Individuals with diabetes have an elevated risk of developing AKI. However, the contribution of ferroptosis to the heightened suscept...
S-EPMC12881128 | biostudies-literature
UnknownThe status of MRI databases across the world focused on psychiatric and neurological disorders.
Neuroimaging databases for neuro-psychiatric disorders enable researchers to implement data-driven research approaches by providing access to rich data that can be used to study disease, build and validate machine learning models, and even redefine disease spectra. The importance of sharing large, m...
S-EPMC11804910 | biostudies-literature
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