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ProteomicsNanochip proteome of Klebsiella
In this study, we used an interdisciplinary approach, combining biophysics and systems biology, to design a microfluidic chip for the multiplexed detection and separation of pathogen cells from immune cells combined with proteomic profiling using mass spectrometry. Our nanochip design includes preci...
ORGANISM(S): Klebsiella pneumoniae subsp. pneumoniae 
2026-03-21 | PXD058426 | Pride
Quantitative proteomics Microfluidics Klebsiella pneumoniae Nanochip technology Macrophages Anti-virulence Systems biology 
UnknownDirect observation and analysis of TET-mediated oxidation processes in a DNA origami nanochip.
Not available
S-EPMC7192588 | biostudies-literature
ProteomicsCoupling microdroplet-based sample preparation, multiplexed isobaric labeling, and nanoflow peptide fractionation for deep proteome profiling of tissue microenvironment
Existing spatially-resolved proteomics technologies cannot provide deep proteome coverage due to limited sensitivity and poor sample recovery. Herein, we seamlessly combined laser capture microdissection with a low-volume sample processing technology that includes a microfluidic device named microPO...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-01-25 | MSV000093925 | MassIVE
UnknownMolecular and functional extracellular vesicle analysis using nanopatterned microchips monitors tumor progression and metastasis.
Not available
S-EPMC8024111 | biostudies-literature
UnknownA 3D Plasmonic Crossed-Wire Nanostructure for Surface-Enhanced Raman Scattering and Plasmon-Enhanced Fluorescence Detection.
Not available
S-EPMC7827238 | biostudies-literature
UnknownElectrochemical Performance of Micropillar Array Electrodes in Microflows.
Not available
S-EPMC7570346 | biostudies-literature
TranscriptomicsTranscription profiling of rat brain response to baculoviral vector transduction
Recombinant baculoviral vectors efficiently transduce several types of cells in the brain. To characterize host responses to viral challenge, thus verifying the suitability of using the virus for the development of gene therapy strategies in the central nervous system, we used cDNA microarray techno...
ORGANISM(S): Rattus norvegicus 
2008-06-16 | E-GEOD-9833 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of liver from wild type and glucocorticoid receptor knock out mice after dexamethasone treatment
The aim of this study is to identify novel glucocorticoid receptor (GR) regulated hepatic target genes. In order to do so, we used microarray technology to compare the gene expression of wild type and GR-null mice after 3 hrs of dexamethasone treatment.
ORGANISM(S): Mus musculus 
2009-04-30 | E-MEXP-1816 | biostudies-arrayexpress
Transcriptomicssingle cell RNA-seq of microfluidic device enriched circulating tumor cells from small cell lung cancer patients prior or post tarlatamab treatment
This single cell RNA-seq experiment was performed to quantify DLL3 expression in circulating tumor cells in small cell lung cancer patients to predict response to tarlatamab treatment. CTCs enriched from the blood of three SCLC patients prior or post tarlatamab treatment using the CTC-iChip followed...
ORGANISM(S): Homo sapiens 
2025-12-11 | E-MTAB-16413 | biostudies-arrayexpress
TranscriptomicsMouse lung tissue transcriptome response to a mouse-adapted strain of SARS-CoV in wild type C57BL6/NJ mice and TLR3-/- mice
The purpose is to determine the role of TLR3-/- on the regulation of the host immune response during lethal SARS-CoV infection Groups of 10 week old C57BL6/NJ or TLR3-/- mice were infected with MA15 virus at a dose of 10^5 PFU or time-matched mock infected. Time points were 2, 4 and 7 days post in...
ORGANISM(S): Mus musculus 
2015-05-12 | E-GEOD-68820 | biostudies-arrayexpress
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