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ProteomicsInhaled Multi-Walled Carbon Nanotubes modulate differently global gene and protein expression in lung rats (additipon to PXD018900)
Multi-walled carbon nanotubes (MWCNTs) are among the most promising nanomaterials because of their physical and chemical properties. However, since they are biopersistent fiber-like materials which share similarities with asbestos, concerns have arisen about their health effects. With their various ...
ORGANISM(S): Rattus norvegicus (Rat) 
2021-11-22 | PXD029842 | Pride
Nanotubes mwcnts rat lung 
ProteomicsInhaled Multi-Walled Carbon Nanotubes modulate differently global gene and protein expression in lung rats
Multi-walled carbon nanotubes (MWCNTs) are among the most promising nanomaterials because of their physical and chemical properties. However, since they are biopersistent fiber-like materials which share similarities with asbestos, concerns have arisen about their health effects. With their various ...
ORGANISM(S): Rattus norvegicus (Rat) 
2021-01-04 | PXD018900 | Pride
Multi-walled carbon nanotubes Proteomics Rat Inhalation Transcriptomics 
TranscriptomicsGene expression profiles in rat lung following intratracheal instillation with cellulose nanofibrils and multi-walled carbon nanotubes
To evaluate the biological effects at the transcriptional level of manufactured nanomaterials, whole genome microarray analysis of rat lungs intratracheally instilled with cellulose nanofibrils (CNFs) with different physicochemical properties or multi-walled carbon nanotubes (MWCNTs) were performed.
ORGANISM(S): Rattus norvegicus 
2020-07-09 | GSE154013 | GEO
TranscriptomicsExtensive temporal transcriptome and microRNA analyses identify molecular mechanisms underlying mitochondrial dysfunction induced by multi-walled carbon nanotubes in human lung cells (miRNA)
Understanding toxicity pathways of engineered nanomaterials (ENM) has recently been brought forward as a key step in 21st century ENM risk assessment. Molecular mechanisms linked to phenotypic end points is a step towards the development of toxicity tests based on key events, which may allow for gro...
ORGANISM(S): Homo sapiens 
2015-04-02 | E-GEOD-63559 | biostudies-arrayexpress
TranscriptomicsExtensive temporal transcriptome and microRNA analyses identify molecular mechanisms underlying mitochondrial dysfunction induced by multi-walled carbon nanotubes in human lung cells (Affymetrix)
Understanding toxicity pathways of engineered nanomaterials (ENM) has recently been brought forward as a key step in 21st century ENM risk assessment. Molecular mechanisms linked to phenotypic end points is a step towards the development of toxicity tests based on key events, which may allow for gro...
ORGANISM(S): Homo sapiens 
2015-04-02 | E-GEOD-63552 | biostudies-arrayexpress
GenomicsGene expression profiles in rat lung following intratracheal instillation with cellulose nanofibrils and multi-walled carbon nanotubes
Gene expression profiles in rat lung following intratracheal instillation with cellulose nanofibrils and multi-walled carbon nanotubes
PRJNA644821 | ENA
TranscriptomicsGene expression profiles in rat lung following intratracheal instillation with short size single-wall and multi-wall carbon nanotubes
To further development of our gene expression approach to assess the effects of manufactured nanomaterials at the transcriptional level, we have employed whole genome microarray expression profiling to discuss the differences of the pulmonary and pleural Groups of nine-week-old male Wistar rats (n =...
ORGANISM(S): Rattus norvegicus 
2015-11-19 | E-GEOD-75148 | biostudies-arrayexpress
UnknownLong-term retention of pristine multi-walled carbon nanotubes in rat lungs after intratracheal instillation.
Not available
S-EPMC4784168 | biostudies-literature
UnknownOsteopontin mRNA expression by rat mesothelial cells exposed to multi-walled carbon nanotubes as a potential biomarker of chronic neoplastic transformation in vitro.
Not available
S-EPMC8085121 | biostudies-literature
TranscriptomicsExtensive temporal transcriptome and microRNA analyses identify molecular mechanisms underlying mitochondrial dysfunction induced by multi-walled carbon nanotubes in human lung cells
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2015-04-02 | E-GEOD-63580 | biostudies-arrayexpress
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