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TranscriptomicsPho85, Pcl1, and Hms1 Signaling Governs Candida albicans Morphogenesis Induced by Elevated Temperature or Hsp90 Compromise
This SuperSeries is composed of the following subset Series: GSE34255: Pho85, Pcl1, and Hms1 Signaling Governs Candida albicans Morphogenesis Induced by Elevated Temperature or Hsp90 Compromise [mRNA] GSE34938: Pho85, Pcl1, and Hms1 Signaling Governs Candida albicans Morphogenesis Induced by Elevate...
ORGANISM(S): Candida albicans 
2012-03-20 | E-GEOD-34939 | biostudies-arrayexpress
TranscriptomicsConjugated linoleic acid inhibits hyphal growth in Candida albicans by modulating Ras1 cellular levels and down-regulating TEC1 expression
The polymorphic yeast Candida albicans exists in blastospore and filamentous forms. The switch from one morphological state to the other coincides with the expression of virulence factors, which makes the yeast-to-hypha transition an attractive target for the development of new antifungal agents. Be...
ORGANISM(S): Candida albicans 
2011-03-10 | E-GEOD-25822 | biostudies-arrayexpress
TranscriptomicsPho85, Pcl1, and Hms1 Signaling Governs Candida albicans Morphogenesis Induced by Elevated Temperature or Hsp90 Compromise [mRNA]
The capacity to sense and transduce temperature signals pervades all aspects of biology, and temperature exerts powerful control over the development and virulence of diverse pathogens. In the leading fungal pathogen of humans, Candida albicans, temperature has a profound impact on morphogenesis, a ...
ORGANISM(S): Candida albicans 
2012-03-20 | E-GEOD-34255 | biostudies-arrayexpress
TranscriptomicsPho85, Pcl1, and Hms1 Signaling Governs Candida albicans Morphogenesis Induced by Elevated Temperature or Hsp90 Compromise [ChIP-chip]
The capacity to sense and transduce temperature signals pervades all aspects of biology, and temperature exerts powerful control over the development and virulence of diverse pathogens. In the leading fungal pathogen of humans, Candida albicans, temperature has a profound impact on morphogenesis, a ...
ORGANISM(S): Candida albicans 
2012-03-20 | E-GEOD-34938 | biostudies-arrayexpress
TranscriptomicsDepletion of the Cullin Cdc53p Induces Morphogenetic Changes in Candida albicans
Transcriptional profiling of CDC53 down-regulated Candida albicans cells compared to control cells Keywords: comparative genomic hybridization, genetic modification Candida albicans is an important opportunistic human fungal pathogen, which can cause mucosal as well as systemic infections in immun...
ORGANISM(S): Candida albicans 
2010-05-14 | E-GEOD-13976 | biostudies-arrayexpress
Transcriptomicsgene expression profiling of brain metastatic melanoma cell lines
Cerebral metastases occur in a majority of metastatic melanoma patients and are a major cause of mortality. Despite this, there is a poor understanding of the molecules/pathways that lead to the brain-metastatic phenotype. Studies designed to address this deficiency and test novel therapeutic approa...
ORGANISM(S): Homo sapiens 
2012-11-21 | E-GEOD-23601 | biostudies-arrayexpress
TranscriptomicsTranscriptional Response of Candida albicans Cells Following Phagocytosis by Mouse Macrophages
Transcriptional profiling of Candida albicans that had been phagocytosed for 1, 2, or 4 hours by either bone marrow-derived mouse macrophaged (BMDM) or immortalized RAW264.7 cells Keywords: Time course Two-condition experiment, phagocytosed cells vs cells maintained in D-10 media. Time course: 1, 2,...
ORGANISM(S): Candida albicans 
2008-07-28 | E-GEOD-11399 | biostudies-arrayexpress
UnknownMolecular Characterization of the Vasculature of Patients with Infiltrating Ductal Carcinoma generates a Gene Signature predictive of Breast Cancer Survival
Not available
ORGANISM(S): Homo sapiens 
S-ECPF-GEOD-43379 | biostudies-other
TranscriptomicsFunctions of the Mediator subunit Med31 in Candida albicans support a role in shaping species-specific gene expression.
Mediator is an essential, evolutionarily conserved co-regulator of RNA polymerase II. Studies in model yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe showed remarkably conserved roles for Mediator despite high species divergence, and thus whether Mediator contributed to establishment ...
ORGANISM(S): Candida albicans 
2012-02-20 | E-GEOD-31632 | biostudies-arrayexpress
TranscriptomicsFunctional control of the Candida albicans cell wall by catalytic protein kinase A subunit Tpk1
The cyclic AMP-protein kinase A pathway has a central role in the biology of Candida albicans, a prominent fungal pathogen of humans. The two catalytic subunits for cyclic AMP-dependent protein kinase, Tpk1 (orf19.4892) and Tpk2 (orf19.2277), have divergent roles, and most studies indicate a more pr...
ORGANISM(S): Candida albicans 
2012-08-06 | E-GEOD-38846 | biostudies-arrayexpress
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