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ProteomicsThe HDAC inhibitor SAHA regulates CBX2 stability via a SUMO-triggered ubiquitin-mediated pathway in leukemia
Leukemias are characterized by bone marrow failure due to oncogenic mutations of hematopoietic stem cells (HSC) or blood precursor cells. HSC differentiation and self-renewal properties are tightly regulated by Polycomb group (PcG) proteins, a well-characterized family of transcriptional epigenetic ...
ORGANISM(S): Homo sapiens (Human) 
2018-02-27 | PXD008287 | Pride
Saha Sumoylation Leukemia Cbx2 
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