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Changes in protein expression drive both the acute responses and long-lasting adaptation of cells to internal and external stimuli. While advances in labelling strategies have made it possible to examine general proteome dynamics, it is still not possible to access the proteomes of specific cell typ...
ORGANISM(S): Mus musculus (Mouse) 
2017-11-10 | PXD007703 | Pride
We have characterized the responses of the opportunistic pathogen Pseudomonas aeruginosa to prolonged starvation for carbon or nitrogen sources, and to transitions between these states. We find that most cells survive both types of starvation for more than a week and maintain low but robustly detect...
ORGANISM(S): Pseudomonas aeruginosa (strain UCBPP-PA14) Bacteria 
2026-03-04 | PXD069190 | Pride
Nascent polypeptide within the exit tunnel stabilizes the ribosome to counteract risky translation
Continuous translation elongation, irrespective of amino acid sequences, is a prerequisite for living organisms to produce their proteomes. However, the risk of elongation abortion is concealed within nascent polypeptide products. For example, negatively charged sequences with occasional intermitten...
ORGANISM(S): Escherichia coli 
2021-12-08 | GSE184331 | GEO
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