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GenomicsExploring the Landscape of Microproteins in T Cells: Insights Gained from Nascent Protein Profiling and Global Proteomics Approaches
Exploring the Landscape of Microproteins in T Cells: Insights Gained from Nascent Protein Profiling and Global Proteomics Approaches
PRJNA1162571 | ENA
UnknownNascent chromatin capture proteomics determines chromatin dynamics during DNA replication and identifies unknown fork components.
Not available
S-EPMC4283098 | biostudies-literature
UnknownGroEL/ES chaperonin unfolds then encapsulates a nascent protein on the ribosome.
Not available
S-EPMC12615815 | biostudies-literature
TranscriptomicsExploring the Landscape of Microproteins in T Cells: Insights Gained from Nascent Protein Profiling and Global Proteomics Approaches
Microproteins, as hidden players in the proteomic club, are encoded by small open reading frames (sORFs) and have garnered increasing attention in recent years. T cells play a critical role in the immune system's response to cancer, however, the exploration of novel microproteins in T cells remains ...
ORGANISM(S): Homo sapiens 
2024-09-24 | GSE277522 | GEO
ProteomicsNascent Ribo-Seq measures ribosomal loading time and reveals kinetic impact on ribosome density
mRNAs are generally assumed to be loaded instantly with ribosomes upon entry into the cytoplasm. To measure ribosome density on nascent mRNA, we developed nascent Ribo-Seq (nRibo-Seq) by combining Ribo-Seq with progressive 4-thiouridine labelling. In mouse macrophages, we experimentally determined, ...
ORGANISM(S): Mus musculus (Mouse) 
2021-06-22 | PXD026828 | Pride
Ribo-seq Translatome Nascent peptides 
UnknownRevealing nascent proteomics in signaling pathways and cell differentiation.
Not available
S-EPMC5877968 | biostudies-literature
ProteomicsNascent proteome reveals key regulators in the development of alcoholic liver disease
Alcoholic liver disease (ALD) poses a significant global health challenge, and the global proteome will change dynamically and dramatically for the response to alcohol stress. However, due to the lack of method for labeling and identification of tissue-specific nascent proteome in living mouse, the ...
ORGANISM(S): Homo Sapiens Mus Musculus 
PXD051725 |
ProteomicsLipid mediated–phase separation of AGO proteins on the ER controls nascent peptide ubiquitination
we sought to determine whether dmAGO1 and Ltn1 share common ubiquitinated nascent peptide targets. For this purpose, we performed the UBA bead-based immunoprecipitation followed by mass spec experiments to identify the ubiquitinated nascent peptide targets of dmAGO1 and Ltn1, respectively. In this a...
ORGANISM(S): Drosophila Melanogaster 
2022-02-18 | PXD031749 |
ProteomicsThe beta subunit of nascent polypeptide associated complex plays a role in flowers and siliques development of Arabidopsis thaliana
The nascent polypeptide-associated (NAC) complex was described in yeast as a heterodimer composed of two subunits, α and β, and was shown to bind to the nascent polypeptides newly emerging from the ribosome. Although NAC function was widely described in yeast, less is known about its role in plants....
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2020-05-27 | PXD016315 | Pride
Lc-msms Arabidopsis thaliana Flower bud proteome Label-free proteomics Nascent polypeptide-associated complex Small heat shock proteins Stress response Male gametophyte Flower bud transcriptome Differential expression 
ProteomicsA mini-hairpin shaped nascent peptide blocks translation termination by a distinct mechanism
The mini-hairpin shaped nascent peptide that blocks translation termination was found by comprehensive proteomics approach for small ORFs overexpression.
ORGANISM(S): Escherichia Coli 
2025-02-17 | PXD052430 | JPOST Repository
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