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UnknownAge-dependent changes in health status in the Childhood Cancer Survivor cohort.
Not available
S-EPMC4314595 | biostudies-literature
Methylation profiling[E-TABM-482] DNA methylome of human spermatozoa
Genome-wide DNA methylation profile of human spermatozoa using the meDIP technique and massively parallel sequencing. DNA methylation is an indispensible epigenetic modification required for regulating the expression of mammalian genomes. Immunoprecipitation-based methods for DNA methylome analysis ...
ORGANISM(S): Homo sapiens 
2011-02-05 | GSE25686 | GEO
TranscriptomicsTranscription profiling of murine livers after resveratrol treatment of mice on a high-calorie diet
Resveratrol (3,5,4'-trihydroxystilbene) extends the lifespan of diverse species including yeast, worms, and flies. In these organisms, lifespan extension is dependent on Sir2, a conserved deacetylase proposed to underlie the beneficial effects of caloric restriction (CR). Here we show that resveratr...
ORGANISM(S): Mus musculus 
2008-06-21 | E-GEOD-6089 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of E. coli O157:H7 growth in the absence or presence of HEp-2 epithelial cells
E. coli O157:H7 global gene expression profile is altered during growth in the presence of Hep-2 cells, relative to the absence of cells; We used Affymetrix E. coli 2.0 genechips to determine gene expression changes Experiment Overall Design: E. coli O157:H7 total RNA extracts were collected after a...
ORGANISM(S): Escherichia coli O157:H7 
2009-03-28 | E-GEOD-14238 | biostudies-arrayexpress
GenomicsHomo sapiens
[E-TABM-482] DNA methylome of human spermatozoa
PRJNA135835 | ENA
GenomicsMapping Novel Chromatin Regions Using Sono-Seq
We found that sonication of crosslinked chromatin produces breaks at non-random sites in DNA and can be used to map sites of high chromatin accessibility when combined with high-throughput tag sequencing using the GA II platform from Illumina. This technique, which we named Sono-Seq, can be a simple...
ORGANISM(S): Homo sapiens 
2008-12-18 | E-GEOD-14022 | biostudies-arrayexpress
TranscriptomicsCaloric restriction induces heat shock response and inhibits B16F10 cell tumorigenesis both in vitro and in vivo
Caloric restriction (CR) without malnutrition is one of the most consistent strategies for increasing mean and maximal lifespan and delaying the onset of age-associated diseases. Stress resistance is a common trait of many long-lived mutants and life-extending interventions, including CR. Indeed, be...
ORGANISM(S): Mus musculus 
2015-08-06 | E-GEOD-67430 | biostudies-arrayexpress
TranscriptomicsMethylation profiling of human normal somatic tissues, placenta, sperm and an immortalized cell line to identify tissue-specific differentially methylated regions
Genome-wide DNA methylation reference profiles of 13 normal somatic tissues, placenta, sperm and an immortalized cell line using the meDIP technique and a custom oligonucleotide array targetting the vast majority of annotated TSSs and non-promoter CGIs in the human genome.
ORGANISM(S): Homo sapiens 
2008-04-30 | E-TABM-445 | biostudies-arrayexpress
GenomicsDNA methylome of human spermatozoa
Genome-wide DNA methylation profile of human spermatozoa using the meDIP technique and massively parallel sequencing
ORGANISM(S): Homo sapiens 
2008-05-31 | E-TABM-482 | biostudies-arrayexpress
UnknownFunctional diversity among cardiolipin binding sites on the mitochondrial ADP/ATP carrier
Not available
S-SCDT-10_1038-S44318-024-00132-2 | biostudies-other
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