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TranscriptomicsNovel male-biased expression in paralogs of the aphid slilmfast nutrient amino acid transporter expansion
A major goal of molecular evolutionary biology is to understand the fate and consequences of duplicated genes. In this context, aphids are particularly intriguing because the newly sequenced pea aphid genome is characterized by extraordinarily high levels of lineage-specific gene duplication relativ...
ORGANISM(S): Myzus persicae 
2011-09-13 | E-GEOD-31024 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of fiber cell maturation in the lens
The mammalian lens consists of an aged core of quiescent cells enveloped by a layers of mature fully elongated and younger, continuously elongating and transcriptionaly active cells. In the present study, we compared global gene expression profiles in elongating and mature, non-elongating fiber cell...
ORGANISM(S): Mus musculus 
2008-06-22 | E-GEOD-2083 | biostudies-arrayexpress
TranscriptomicsIdentifying gene expression profiles in hypoplastic left heart syndrome and age-matched normal controls
Affymetrix GeneChip Exon-1.0ST was used to study the differential gene profiles in RV (right ventricle) samples from neonates with HLHS (hypoplastic left heart syndrome) versus RV and LV (left ventricle) samples obtained from age-matched controls. Although few significant changes were observed in th...
ORGANISM(S): Homo sapiens 
2011-12-31 | E-GEOD-23959 | biostudies-arrayexpress
TranscriptomicsAchyranthes aspera leaf extract modulates the expression of genes involved in immune response and embryonic development etc in vitro in cultured human pancreatic cancer cell line MIA PaCa-2 (CRL1420).
Examining of the global gene expression changes in cultured human pancreatic cancer cells effected by the extract of A. aspera leaves. Comparison of cells treated for 24, 48 and 72 hours with the respective controls (untreated) allowed to select key genes that may be of interest as a response marker...
ORGANISM(S): Homo sapiens 
2013-12-01 | E-GEOD-44290 | biostudies-arrayexpress
TranscriptomicsInhibition of astroglial NF-kB regulates oligogenesis following spinal cord injury.
Astrocytes are taking the center stage in neurotrauma and neurological disease as they appear to play a dominant role in the inflammatory processes associated with these conditions. Previously, we reported that inhibiting nuclear factor kappa B (NF-kB) activation in astrocytes, by using a transgenic...
ORGANISM(S): Mus musculus 
2013-09-01 | E-GEOD-46695 | biostudies-arrayexpress
TranscriptomicsGenomic signatures of a global fitness index in a multi-ethnic cohort of women
The rates of obesity and sedentary lifestyle are on a dramatic incline, with associated detrimental health effects among women in particular. Although exercise prescriptions are useful for overcoming these problems, success can be hampered by differential responsiveness among individuals in cardiova...
ORGANISM(S): Homo sapiens 
2012-05-31 | E-GEOD-34788 | biostudies-arrayexpress
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