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GenomicsEffect of alisertib and navitoclax on gene expression in B16 melanoma tumors
Effect of alisertib and navitoclax on gene expression in B16 melanoma tumors
PRJNA874062 | ENA
TranscriptomicsEffect of alisertib and navitoclax on gene expression in B16 melanoma tumors
To investigate how tumor cells respond to alisertib and navitoclax single agents and combonation therapy in vivo, mice with melanoma were treated with these agents or vehicle-contol. RNAseq was used to investigate gene expression in tumors
ORGANISM(S): Mus musculus 
2022-10-26 | GSE212127 | GEO
UnknownMulti-Omics Investigation of Innate Navitoclax Resistance in Triple-Negative Breast Cancer Cells.
Not available
S-EPMC7563413 | biostudies-literature
ProteomicsEffects of Navitoclax and Venetoclax on changes in the proteome of mouse pancreas in a mouse model of chronic pancreatitis
Effects of two Bcl-2 protein inhibitors Navitoclax and Venetoclax on changes in the proteome of the mouse pancreas (Mus musculus C57BL6/J, males) in a mouse model of cerulein-induced chronic pancreatitis.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
MSV000095776 | MassIVE
GenomicsTranscriptional activity of a T-ALL PDX line following in vitro treatment with idasanutlin, navitoclax (ABT-263), or combination therapy
Transcriptional activity of a T-ALL PDX line following in vitro treatment with idasanutlin, navitoclax (ABT-263), or combination therapy
PRJNA1003809 | ENA
UnknownNavitoclax Most Promising BH3 Mimetic for Combination Therapy in Hodgkin Lymphoma
Not available
S-EPMC9699187 | biostudies-literature
TranscriptomicsModulation of Navitoclax Sensitivity by Dihydroarteminisin-Mediated MCL-1 Repression
Poor prognosis BCR-ABL+ B-ALL leukemic cells are highly dependent on the expression of endogenous anti-apoptotic MCL-1. However, the survival of most normal blood cells (e.g. progenitors, lymphocytes, and granulocytes) and other normal cell types (e.g. cardiomyocytes and neurons) are also exquisitel...
ORGANISM(S): Mus musculus 
2018-02-14 | GSE95809 | GEO
UnknownNavitoclax (ABT-263) accelerates apoptosis during drug-induced mitotic arrest by antagonizing Bcl-xL.
Not available
S-EPMC3129452 | biostudies-literature
UnknownValidation of a robust and rapid liquid chromatography tandem mass spectrometric method for the quantitative analysis of navitoclax.
Not available
S-EPMC8881338 | biostudies-literature
UnknownNavitoclax combined with Alpelisib effectively inhibits Merkel cell carcinoma cell growth in vitro.
Not available
S-EPMC7739210 | biostudies-literature
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