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GenomicsThe long noncoding RNAs NEAT1 and MALAT1 bind active chromatin sites
Long noncoding RNAs (lncRNAs) are important regulators of chromatin; however, the mechanistic roles for many lncRNAs are poorly understood in part because their direct interactions with genomic loci and proteins are difficult to assess. We used CHART-seq to map the genomic binding sites for two high...
ORGANISM(S): Homo sapiens 
2014-08-12 | E-GEOD-58444 | biostudies-arrayexpress
ProteomicsNEAT1 Regulates BMSCs Aging Through Disruption of FGF2 Nuclear Transport
Background: The aging of bone marrow mesenchymal stem cells (BMSCs) impairs bone tissue regeneration, contributing to skeletal disorders. LncRNA NEAT1 is considered as a proliferative inhibitory role during cellular senescence, but the relevant mechanisms remain insufficient. This study aims to eluc...
ORGANISM(S): Homo Sapiens 
2025-01-16 | PXD059860 |
TranscriptomicsKnockdown of NEAT1 in HepG2 Cells
HepG2 cells were transfected with Gapmers against the NEAT1 ncRNA. THe experimental design inlcudes a negative control by scrabled Gapmers, and combination of Gapmer no.1 and no.3. Total RNA was sequenced after Ribo Depletion.
ORGANISM(S): Homo sapiens 
2026-04-15 | E-MTAB-16823 | biostudies-arrayexpress
ProteomicsIntegrator restraints paraspeckles assembly by promoting the 3’-end processing of the polyadenylated lncRNA NEAT1_1
Alternative 3’-end RNA processing provides an important source of transcriptome diversification, which impacts various biological processes and the etiology of diseases, including cancer. Here, we focused on a transcript isoform switch that leads to the readthrough expression of the long noncoding R...
ORGANISM(S): Homo sapiens (Human) 
2020-10-14 | PXD015158 | Pride
Cancer Neat1  alternative 3’-end rna processing Integrator Paraspeckles 
TranscriptomicsRNA-seq of NEAT1 knockdown in neuronal excitability
We investigated the role of NEAT1 knockdown on neuronal excitability in iPSC-derived neurons.
ORGANISM(S): Homo sapiens 
2017-01-26 | E-MTAB-3447 | biostudies-arrayexpress
GenomicsNEAT1-driven ceRNA network in multiple myeloma
NEAT1-driven ceRNA network in multiple myeloma
PRJNA1301852 | ENA
GenomicsNEAT1 RIP-seq on neural progenitor cells
NEAT1-Mediated Regulation in Rett Syndrome
PRJEB81894 | ENA
GenomicsRNA-Seq results of cervical spinal cords from NEAT1-KO hSOD1G93A mice, compared to NEAT1-WT hSOD1G93A
RNA-Seq results of cervical spinal cords from NEAT1-KO hSOD1G93A mice, compared to NEAT1-WT hSOD1G93A
PRJNA1175346 | ENA
GenomicsKnockdown of NEAT1 in HepG2 Cells
Knockdown of NEAT1 in HepG2 Cells
PRJEB110906 | ENA
GenomicsEffect of NEAT1 modulation on antiviral immune response
Effect of NEAT1 modulation on antiviral immune response
PRJNA862359 | ENA
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