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TranscriptomicsGene expression profile of a S. cerevisiae strain deleted in CSN5/RRI1 gene (systematic name YDL216C)
The COP9 signalosome (CSN) is a highly conserved eukaryotic protein complex which regulates the Cullin-RING family of ubiquitin ligases and carries out a deneddylase activity that resides in subunit 5 (CSN5). The budding yeast CSN is biochemically active and deletion mutants of each of its subunits ...
ORGANISM(S): Saccharomyces cerevisiae 
2013-10-23 | E-GEOD-51563 | biostudies-arrayexpress
TranscriptomicsMouse skin: neutron irradiation
The objective of this investigation was to characterize, at individual level, the transcriptional response and the onset of regenerative processes in mouse skin irradiated with different doses of fast neutrons. We performed a high-throughput gene expression analysis, by DNA oligonucleotide microarra...
ORGANISM(S): Mus musculus 
2010-11-16 | E-GEOD-25343 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of yeast subjected to different concentrations of caesium chloride salt
S. cerevisiae BY4741 (Mata; His3Delta1; leuDelta0; lys2Delta0; ura3Delta0) was grown in YPD at 30 degrees C with aeration to exponential growth phase and was subjected to a different concentrations of Caesium Chloride salt: 0mM, 30mM, 50mM, 100mM, 150mM, 200mM and 250mM 20 minutes at 30 degrees C.
ORGANISM(S): Saccharomyces cerevisiae 
2007-11-01 | E-MEXP-1292 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of yeast knockouts: DAL82, PDR3, UGA3 vs wild type
Isogenic YAF9+ or yaf91- yeast strains were treated with Caesium Chloridesalt. Targets were obtained from 3 Caesium Chloride concentration points: 0mM, 100mM and 150mM. Two biological replicates of each were generated and the expression profiles were determined using Yeast double genome DNA...
ORGANISM(S): Saccharomyces cerevisiae 
2007-10-31 | E-MEXP-1293 | biostudies-arrayexpress
TranscriptomicsVector-transduced neurons transcriptome profiles
With the goal of specifically dissecting the toxicogenomic signatures of the helper-dependent (HD) human (HAd5) and canine (CAV-2) adenovirus, the VSV-G-pseudotyped SIN HIV-1 (LV) and the Adenoviral-associated vector 2/9 for human neurons (AAV2/9), we transduced a bona fide human neuronal system wit...
ORGANISM(S): Homo sapiens 
2013-05-22 | E-GEOD-47130 | biostudies-arrayexpress
TranscriptomicsCAV-2 vector-transduced human neurospheres transcriptome profiles
Brain gene transfer using viral vectors will likely become a therapeutic option for several disorders. Helper-dependent (HD) canine adenovirus type 2 vectors (CAV-2) are well suited for this goal. Indeed, these vectors are poorly immunogenic, efficiently transduce neurons, are retrogradely transport...
ORGANISM(S): Homo sapiens 
2014-10-24 | E-GEOD-62687 | biostudies-arrayexpress
UnknownColchicine treatment in amyotrophic lateral sclerosis: safety, biological and clinical effects in a randomized clinical trial.
Not available
S-EPMC11406549 | biostudies-literature
UnknownThe density and spatial tissue distribution of CD8+ and CD163+ immune cells predict response and outcome in melanoma patients receiving MAPK inhibitors.
Not available
S-EPMC6858711 | biostudies-literature
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