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TranscriptomicsNon-small-cell lung tumor and normal lung tissue methylation
Using paired tumor and non-tumor lung tissues from 47 individuals we identified common changes in DNA methylation associated with the development of non-small cell lung cancer. Pathologically normal lung tissue taken at the time of cancer resection was matched to tumorous lung tissue and together we...
ORGANISM(S): Homo sapiens 
2012-07-02 | E-GEOD-27902 | biostudies-arrayexpress
TranscriptomicsIDH1 mutation defines methylation class and survival in human glioma
Astrocytoma, oligodendroglioma, oligoastrocytoma, and ependymoma are the main histologic subtypes of glioma. The molecular character of these subtypes has profound implications for understanding their causes and treatment. We describe the epigenetic landscape of these tumor types using novel DNA met...
ORGANISM(S): Homo sapiens 
2010-12-20 | E-GEOD-20395 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of muscle gene expression in response to an intense cycling exercise. Effect of two protein-leucine enriched diets
Protein-leucine supplement ingestion following strenuous endurance exercise accentuates skeletal-muscle protein synthesis and adaptive molecular responses, but the underlying transcriptome is uncharacterized. In a randomized single-blind triple-crossover design, 12 trained men completed 100 min of h...
ORGANISM(S): Homo sapiens 
2015-11-23 | E-GEOD-44818 | biostudies-arrayexpress
UnknownSPP1 is required for maintaining mesenchymal cell fate in pancreatic cancer.
Not available
S-EPMC12675285 | biostudies-literature
TranscriptomicsColon tumor samples
In response to polarization cues, cultured Caco-2 cells, a human colon adenocarcinoma-derived cell line, form a polarized epithelium resembling normal enterocytes. We investigated potential signaling mechanisms activated by Caco-2 cells that might trigger the genome-wide transcriptional reprogrammi...
ORGANISM(S): Homo sapiens 
2007-08-17 | E-GEOD-7466 | biostudies-arrayexpress
TranscriptomicsIdentification of SULF2 as a novel transcriptional target of p53 by use of integrated genomic analyses.
Microarray analysis has been useful for identifying the targets of many transcription factors. However, gene expression changes in response to transcription factor perturbation reveal both direct transcriptional targets and secondary gene regulation. By integrating RNA interference, gene expression ...
ORGANISM(S): Homo sapiens 
2010-06-20 | E-GEOD-15440 | biostudies-arrayexpress
UnknownDiverse values of nature for sustainability.
Not available
S-EPMC10447232 | biostudies-literature
UnknownEffect of decentralising childhood tuberculosis diagnosis to primary health centre versus district hospital levels on disease detection in children from six high tuberculosis incidence countries: an operational research, pre-post intervention study.
Not available
S-EPMC11056389 | biostudies-literature
UnknownGlobal assessment of marine plastic exposure risk for oceanic birds.
Not available
S-EPMC10319801 | biostudies-literature
UnknownVulnerability of marine megafauna to global at-sea anthropogenic threats.
Not available
S-EPMC12856791 | biostudies-literature
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