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Bare-metal (BMS) and drug-eluting stents (DES) were implanted in pig coronary arteries with an overstretch during coronary angioplasty under optical coherence tomography guidance. Arteries subjected to plain old balloon angioplasty (POBA) alone served as controls. Stented/balloon dilated segments we...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2017-11-24 | PXD005726 | Pride
EHMT1/KMT1D drives neointima formation via epigenetic repression of the PPARγ–PDIA6 axis
We tried to identify mRNA targets of miR-126 involved in neointima formation in mice with an atherogenic background. Genome-wide expression profiling was carried out in wire-injured carotid arteries of miR-126+/+/ApoE-/- (control group) and miR-126-/-/ApoE-/- (target group) mice on western-type diet...
ORGANISM(S): Mus musculus 
Transcriptomic profiling of human saphenous veins during ex vivo culture–induced neointima proliferation
In order to identify microRNAs involved in neointima formation in mice with an atherogenic background, wire-induced carotid injury was performed in ApoE-/- mice on western-type diet. Uninjured carotid arteries served as control. RNA was isolated after 1, 7, 14, and 28 days (n=3-4 each group) and hyb...
ORGANISM(S): Mus musculus 
2014-11-28 | GSE34054 | GEO
Neointima formation underlies restenosis and other occlusive vascular diseases, yet the epigenetic regulators that drive this process remain poorly understood. We aimed to define the role of the histone methyltransferase EHMT1 in neointima formation and to delineate its downstream mechanisms. Here, ...
ORGANISM(S): Homo sapiens 
2026-07-13 | GSE333141 | GEO
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