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TranscriptomicsExpression data from A2780 (cisplatin-sensitive) and Round5 A2780 (cisplatin-resistant) cell lines.
Cisplatin and carboplatin are the primary first-line therapies for the treatment of ovarian cancer. However, resistance to these platinum-based drugs occurs in the large majority of initially responsive tumors, subsequently resulting in a poor long-term prognosis. To model the onset of drug resista...
ORGANISM(S): Homo sapiens 
2009-04-17 | E-GEOD-15372 | biostudies-arrayexpress
TranscriptomicsExpression and metylation data from A2780 (cisplatin-sensitive) and Round5 A2780 (cisplatin-resistant) cell lines
This SuperSeries is composed of the following subset Series: GSE15372: Expression data from A2780 (cisplatin-sensitive) and Round5 A2780 (cisplatin-resistant) cell lines. GSE15373: Promoter CpG island methylation data from A2780 (cisplatin-sensitive) and Round5 A2780 (cisplatin-resistant) cell lines...
ORGANISM(S): Homo sapiens 
2009-04-17 | E-GEOD-15709 | biostudies-arrayexpress
UnknownAdenoviral-delivered HE4-HSV-tk sensitizes ovarian cancer cells to ganciclovir.
Not available
S-EPMC4440683 | biostudies-literature
GenomicsNext Generation Sequencing Facilitates Quantitative Analysis of effect of knockdown of GATA2 on AR binding sites
Purpose: Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular pathways. The goals of this study are to compare AR binding activity in LNCaP cells with and without knockdown of GATA2. Methods: LNCaP cells between passage number 32-34 were used for assay. Cells are tr...
ORGANISM(S): Homo sapiens 
2014-01-21 | E-GEOD-52725 | biostudies-arrayexpress
UnknownClaudin-4 remodeling of nucleus-cell cycle crosstalk maintains ovarian tumor genome stability and drives resistance to genomic instability-inducing agents.
Not available
S-EPMC11398366 | biostudies-literature
TranscriptomicsTranscription profiling of breast tumors and surrounding tissue to detect pre-malignant histological and genetic changes
The aim of our study is to examine the region of tissue surrounding or adjacent to breast tumor in order to detect pre-malignant histological and genetic changes that may be predictive of risk of breast cancer. In this study, histological and gene expression data of breast tissue were obtained from...
ORGANISM(S): Homo sapiens 
2008-04-13 | E-TABM-276 | biostudies-arrayexpress
UnknownQuality of Life and Adverse Events: Prognostic Relationships in Long-Term Ovarian Cancer Survival.
Not available
S-EPMC8486331 | biostudies-literature
UnknownChronic wound repair and healing in older adults: current status and future research.
Not available
S-EPMC4414710 | biostudies-literature
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