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MetabolomicsTissue, urine and serum NMR metabolomics dataset from a 5/6 nephrectomy rat model of chronic kidney disease

Serum, urine and tissue from a rat model of chronic kidney disease (CKD) were analysed using nuclear magnetic resonance (NMR) spectroscopy-based metabolomics methods, and compared with samples from sham operated rats. Both urine and serum were sampled at multiple timepoints, and the results have ...

2020-11-16 | MTBLS2052 | MetaboLights
TranscriptomicsTranscription profiling of mouse lung to investigate effects of ischemia reperfusion injury or nephrectomy
Experiments in rodents have shown that kidney ischemia/reperfusion injury (IRI) facilitates lung injury and inflammation. To identify potential ischemia-specific lung molecular pathways involved, we conducted global gene expression profiling of lung 6 or 36 hours following 1) bilateral kidney IRI, 2...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-6730 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of laparoscopic donor nephrectomy samples compared to healthy control kidneys
We compared gene expression profiles from six donor kidneys prior to surgical manipulation to six kidneys removed after laparoscopic donor nephrectomy (LDN) and several hours of CO2 pneumoperitoneum. Biopsies were obtained from renal cortex and hybridized to Affymetrix HG-U133A GeneChips. For cont...
ORGANISM(S): Homo sapiens 
2005-09-14 | E-GEOD-3297 | biostudies-arrayexpress
GenomicsTranscriptomic changes in response to 5/6 or 1/3 nephrectomy
Transcriptomic changes in response to 5/6 or 1/3 nephrectomy
PRJNA800379 | ENA
GenomicsComparison of transcriptome landscape between adenine-induced and nephrectomy-induced uremic cardiomyopathy
Comparison of transcriptome landscape between adenine-induced and nephrectomy-induced uremic cardiomyopathy
PRJNA1136533 | ENA
GenomicsThe changes of Chromatin Accessibiliy Triggered by Unilateral Nephrectomy [ATAC-seq]
The changes of Chromatin Accessibiliy Triggered by Unilateral Nephrectomy [ATAC-seq]
PRJNA868703 | ENA
GenomicsDifferently expressed genes of the heart from sham and 5/6 nephrectomy mice
Differently expressed genes of the heart from sham and 5/6 nephrectomy mice
PRJNA598871 | ENA
ProteomicsInvestigation of Resistant Starch effect on gut microbiome in 5/6 nephrectomy mouse model of Chronic Kidney Disease
Background. Resistant Starch (RS) improves CKD outcomes. In this report we study how RS modulates host-microbiome interactions in CKD by measuring changes in abundance of proteins and bacteria in the gut. In addition, we demonstrate RS-mediated reduction in CKD-induced kidney damage. Methods. Eight...
ORGANISM(S): Mus musculus (Mouse) 
2020-10-19 | PXD019623 | Pride
Mouse Microbiome Kidney Metaproteomics 
GenomicsTranscriptome Changes of Microdissected Kidney Tubules triggered by Unilateral Nephrectomy [RNA-seq]
Transcriptome Changes of Microdissected Kidney Tubules triggered by Unilateral Nephrectomy [RNA-seq]
PRJNA868702 | ENA
TranscriptomicsTranscriptomic changes in response to 5/6 or 1/3 nephrectomy
We report the changes in kidney mRNA abundance in response to 5/6 nephrectomy or 1/3 nephrectomy surgery when compared to sham operated controls.
ORGANISM(S): Rattus norvegicus 
2022-03-01 | GSE194367 | GEO
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