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ProteomicsProteomic analysis of isolated nerve terminals from NaV1.9 knockout mice reveals pathways relevant for pain signaling
Chronic pain substantially affects the mental and physical well-being of patients and magnifies the socio-economic burden on the healthcare system. It is important to understand the molecular mechanisms underlying chronic pain to effectively target it. To investigate peripheral mechanisms relevant t...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2025-11-24 | PXD055516 | Pride
Proteomics 
ProteomicsImpaired presynaptic proteostasis in the initial stages of amyloid beta proteotoxicity
Compromised protein homeostasis underlies accumulation of plaques and tangles in Alzheimers disease (AD); however, little is known about the early mechanisms that contribute to this accumulation. To objectively assess the impaired protein turnover at early stages of amyloid beta (Abeta) proteotoxic...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2020-02-24 | MSV000085004 | MassIVE
ProteomicsSynaptic transmission induces site specific changes in sialylation on N-linked glycoproteins in nerve terminals
Synaptic transmission is an ultra-fast process that aims at transducing a signal from one neuron to another neuron or cell by the release of neurotransmitters. This process requires rapid response which can be transmitted through fast molecular switches such as post-translational modifications of pr...
ORGANISM(S): Rattus norvegicus (Rat) 
2020-06-12 | PXD016230 | Pride
Synaptic transmission Sialic acid N-glycosylation Rat Synaptosomes Lc-ms/ms 
ProteomicsAtg9 resides on a unique population of small vesicles in presynaptic nerve terminals
In neurons, autophagosomes are mainly initiated in distal axons, followed by maturation during retrograde transport. Autophagosomal growth depends on the supply of membrane lipids which requires small vesicles containing Atg9, a lipid scramblase essential for autophagocytosis. Here, we show that Atg...
ORGANISM(S): Rattus norvegicus (Rat) 
2024-01-17 | PXD041702 | Pride
Neurons Immunoisolation Atg9 
UnknownELKS1 Captures Rab6-Marked Vesicular Cargo in Presynaptic Nerve Terminals.
Not available
S-EPMC7360120 | biostudies-literature
UnknownPalmitoylethanolamide inhibits glutamate release in rat cerebrocortical nerve terminals.
Not available
S-EPMC4394492 | biostudies-literature
UnknownPresynaptic external calcium signaling involves the calcium-sensing receptor in neocortical nerve terminals.
Not available
S-EPMC2797309 | biostudies-literature
UnknownMorphology of Schwann Cell Processes Supports Renal Sympathetic Nerve Terminals With Local Distribution of Adrenoceptors.
Not available
S-EPMC9284235 | biostudies-literature
UnknownMitochondrial phosphagen kinases support the volatile power demands of motor nerve terminals.
Not available
S-EPMC10841428 | biostudies-literature
UnknownDifferential targeting of dynamin-1 and dynamin-3 to nerve terminals during chronic suppression of neuronal activity.
Not available
S-EPMC4584186 | biostudies-literature
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