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ProteomicsThe jasmonate regulome: Reconstructing a hormone signalling pathway from transcription factor activity to phenotypic outputs
We have investigated the genome regulatory network that controls responses to the hormone jasmonate in seedlings. There is much interest currently in understanding the systems-level actions of transcription factors. However, such studies can provide much greater biological insight if set in the cont...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2020-03-19 | PXD013592 | Pride
Arabidopsis thaliana Regulome Jasmonic acid Myc2 
UnknownA transcription factor hierarchy defines an environmental stress response network.
Not available
S-EPMC5217750 | biostudies-literature
GenomicsWidespread Dynamic DNA Methylation in Response to Biotic Stress
Regulation of gene expression by DNA methylation is crucial for defining cellular identities and coordinating organism-wide developmental programs in many organisms. In plants, modulation of DNA methylation in response to environmental conditions represents a potentially robust mechanism to regulate...
ORGANISM(S): Arabidopsis thaliana 
2012-05-15 | E-MTAB-4226 | biostudies-arrayexpress
GenomicsDistinct epigenomic landscapes of pluripotent and lineage-committed human cells
Human embryonic stem cells share identical genomic sequences with other lineage-committed cells yet possess the remarkable properties of self-renewal and pluripotency. It has been proposed that epigenetic regulatory mechanisms, involving DNA methylation and various chromatin modifications, are at l...
ORGANISM(S): Homo sapiens 
2009-10-13 | E-GEOD-17917 | biostudies-arrayexpress
GenomicsChromatin States in Human ES Cells Reveal Key Regulatory Sequences and Genes Involved in Pluripotency and Self-renewal
Human embryonic stem cells (hESCs) are offering a new therapeutic approach because of their unique ability to proliferate indefinitely in vitro and differentiate into multiple cell types. However, our understanding of the molecular mechanisms of pluripotency and self-renewal remain incomplete. To el...
ORGANISM(S): Homo sapiens 
2009-10-14 | E-GEOD-18292 | biostudies-arrayexpress
TranscriptomicsPatterns of Population Epigenomic Diversity in Arabidopsis thaliana (RNA-Seq)
Natural epigenetic variation provides a source for the generation of phenotypic diversity, but to understand its contribution to phenotypic diversity, its interaction with genetic variation requires further investigation. Here, we report population-wide DNA sequencing of genomes, transcriptomes, and...
ORGANISM(S): Arabidopsis thaliana 
2013-03-05 | E-GEOD-43858 | biostudies-arrayexpress
UnknownIntegrated multi-omics framework of the plant response to jasmonic acid.
Not available
S-EPMC7094030 | biostudies-literature
UnknownTherapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19.
Not available
S-EPMC8362594 | biostudies-literature
UnknownTherapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19.
Not available
S-EPMC8362592 | biostudies-literature
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