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Background Adenosine Deaminase 2 Deficiency (DADA2) is an autoinflammatory disease characterized by systemic vasculopathy, strokes and mild immunodeficiency. Recently NETosis has been implicated in the pathogenesis of Deficiency of Adenosine Deaminase 2. Objectives To deep investigate the possible e...
ORGANISM(S): Homo sapiens (Human) 
2025-06-23 | PXD055246 | Pride
The effect of neutrophil extracellular trap (NETs) on BMDMs
Neutrophils are necessary in mamalian’s life and are the most abundant type of white blood cells in humans with biological roles relevant to inflammation and the entire host response. The release of neutrophil extracellular DNA in innate immune cells provides specific response to bacteria and fungi....
ORGANISM(S): Homo sapiens (Human) 
2022-10-25 | PXD016143 | Pride
Neutrophils have an important role in rapid antimicrobial defenses against and resolution of urinary tract infections (UTIs). We show that a mechanism known as neutrophil extracellular trap (NET) formation is a strategy to combat pathogens in the urinary tract. Viscous aggregates that were present i...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-31 | MSV000080847 | MassIVE
Estrogen-induced NETs promote aseptic inflammation via NKCC1 [human]
Background: Osteoporosis and diabetes represent major global public health challenges. Neutrophil extracellular traps (NETs) serve as key components of the innate immune system by capturing bacteria, fungi, and parasites, thereby trapping them in local environments with high concentrations of antimi...
ORGANISM(S): Homo sapiens 

Objective: Metabolite abnormalities are potentially implicated in pathogenesis of Hashimoto’s thyroiditis (HT). An in-depth study of the relationship between HT and small molecule metabolites, as well as its pathogenesis, can help enhance the diagnosis, prognosis, and treatment of HT patients.

2025-10-12 | MTBLS12333 | MetaboLights
Fucoidan reduces NETs accumulation and alleviates chemotherapy-induced peripheral neuropathy
RNA Sequencing reveals transcriptome profiling of HUVECs in response to NETs ± defibrotide
microRNA profiling in different grading of gastroenteropancreatic neuroendocrine tumors (GEP-NETs)
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