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TranscriptomicsTranscription profiling of rat colon exposed to soy or whey proteins
We previously reported that lifetime consumption of soy proteins or whey proteins reduced the incidence of azoxymethane (AOM)-induced colon tumors in rats. To obtain insights into these effects, global gene expression profiles of colons from rats with lifetime ingestion of casein (CAS, control diet)...
ORGANISM(S): Rattus norvegicus 
2009-04-30 | E-GEOD-6102 | biostudies-arrayexpress
TranscriptomicsHER2 expression identifies dynamic functional states within circulating breast cancer cells
Circulating tumour cells in women with advanced oestrogen-receptor (ER)-positive/human epidermal growth factor receptor 2 (HER2)-negative breast cancer acquire a HER2-positive subpopulation after multiple courses of therapy. In contrast to HER2-amplified primary breast cancer, which is highly sensit...
ORGANISM(S): Homo sapiens 
2016-08-25 | E-GEOD-75367 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of yeast under conditions of ammonium, L-alanine or L-glutamine limitation
Response of Saccharomyces cerevisiae to Ammonium, L-alanine, or L-glutamine Limitation. The protrotophic laboratory strain CEN.PK113-7D (MAT a) was grown in laboratory fermentors with a working volume of 1 litre at dilution rate (D) of 0.20 per hour (in triplicate for each nitrogen limited condition...
ORGANISM(S): Saccharomyces cerevisiae 
2006-06-13 | E-MEXP-724 | biostudies-arrayexpress
TranscriptomicsscRNA-seq analysis of lung neutrophils from mice, 24 hours after intranasal exposure to vehicle, 100 ng LPS and 10 µg LPS
Mice intranasally exposed to a low dose of LPS (i.e., 100 ng) are prone to develop features of allergic asthma upon subsequent exposure to house dust mites (HDM) allergens, while mice exposed to vehicle or 100 µg LPS do not develop such features. In order to understand the mechanisms that promote al...
ORGANISM(S): Mus musculus 
2019-07-25 | E-MTAB-6902 | biostudies-arrayexpress
TranscriptomicsIdentification of differentially expressed genes between clinical and bovine-biased Escherichia coli O157:H7 genotypes
Escherichia coli O157:H7 strains have been classified into different genotypes based on the presence of specific shiga toxin-encoding bacteriophage insertion sites. Genotypes that are predominant in clinical isolates are named clinical genotypes and those that are isolated mostly from bovine source...
ORGANISM(S): Escherichia coli 
2010-06-19 | E-GEOD-15783 | biostudies-arrayexpress
TranscriptomicsBreast Cancer Gene Expression Data from Frankfurt Series
Pooling of microarray datasets seems to be a reasonable approach to increase sample size when a heterogeneous disease like breast cancer is concerned. Different methods for the adaption of datasets have been used in the literature. We have analyzed influences of these strategies using a pool of 3,03...
ORGANISM(S): Homo sapiens 
2014-10-14 | E-GEOD-4611 | biostudies-arrayexpress
TranscriptomicsIL6 Related Cytokines Augment Angiogenesis in Nascent and Mature Human Endothelium Via JAK2 Signaling
While therapeutic angiogenesis holds promise for vascular diseases, progress has been limited due to discrepancies in defining adult endothelial progenitors. We have identified and characterized a population of pluripotent derived NRP1+CD34+ nascent endothelial cells, immediately diverged from NRP1+...
ORGANISM(S): Homo sapiens 
2013-12-14 | E-GEOD-44328 | biostudies-arrayexpress
TranscriptomicsOntogenic changes in hematopoietic hierarchy determine pediatric specificity and disease phenotype in fusion oncogene-driven myeloid leukemia - scRNAseq - 2
Paediatric cancers present specific genetic alterations, however the principles underlying their differences to adult cancers are yet unclear. Poor prognosis paediatric myeloid leukaemia fusion oncogenes represent clinically-relevant models to investigate age-specific tumorigenesis. Here, we establi...
ORGANISM(S): Mus musculus 
2019-10-15 | E-MTAB-8360 | biostudies-arrayexpress
TranscriptomicsGenes Differentially Expressed by Aspergillus flavus Strains After Loss of Aflatoxin Production by Serial Transfers
Aflatoxins are carcinogenic fungal secondary metabolites. Levels of aflatoxins in agricultural commodities are stringently regulated by many countries. A cluster of genes is responsible for aflatoxin biosynthesis by Aspergillus flavus and other closely related species. Expression of the clustered af...
ORGANISM(S): Aspergillus flavus 
2010-05-26 | E-GEOD-8185 | biostudies-arrayexpress
TranscriptomicsA Short-Term Study Investigating the Estrogenic Potency of Diethylstilbesterol in the Fathead Minnow (Pimephales promelas): Recovery phase
Diethylstilbestrol (DES) is a synthetic estrogen that has been banned for use in humans, but still is employed in livestock and aquaculture operations in some parts of the world. Detectable concentrations of DES in effluent and surface waters have been reported to range from slightly below 1 to gre...
ORGANISM(S): Pimephales promelas 
2012-09-20 | E-GEOD-36466 | biostudies-arrayexpress
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