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MetabolomicsSNAP25 inhibits glioma progression by regulating synapse plasticity via GLS-mediated glutaminolysis

INTRODUCTION: Neuronal activity regulated by synaptic communication exerts an important role in tumorigenesis and progression in brain tumors. Genes for soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) annotated with the function ‘vesicle’ about syn...

2021-08-12 | MTBLS2806 | MetaboLights
MetabolomicsFaecal microbiota transplant from aged donor mice affects spatial learning and memory via modulating hippocampal synaptic plasticity- and neurotransmission-related proteins in young recipients

BACKGROUND: The gut-brain axis and the intestinal microbiota are emerging as key players in health and disease. Shifts in intestinal microbiota composition affect a variety of systems, however, evidence of their direct impact on cognitive functions is still lacking. We tested whe...

2021-12-17 | MTBLS1437 | MetaboLights
ProteomicsProteomic analysis of Adnp mutant mice
We report age-differential synaptic plasticity deficits associated with cognitive inflexibility and CaMKIIa hyperactivity in Adnp-mutant mice. These mice show impaired and inflexible contextual learning and memory additional to social and anxiety-related deficits in adults long after a marked decrea...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
MSV000090257 | MassIVE
UnknownNeural Plasticity Is Involved in Physiological Sleep, Depressive Sleep Disturbances, and Antidepressant Treatments.
Not available
S-EPMC5664320 | biostudies-literature
UnknownLanguage and Sensory Neural Plasticity in the Superior Temporal Cortex of the Deaf.
Not available
S-EPMC5954881 | biostudies-literature
TranscriptomicsEmbryonic and adult neural crest stem cells
Cells were isolated from mouse embryonic neural crest stem cells at culture day 2 (NCSC), from day 7 in vitro differentiated progeny (NCP) and day 2 epidermal neural crest stem cells from bulge explants of adult whisker follicles (EPI-NCSC). Keywords: LongSAGE embryonic neural crest stem cells at cu...
ORGANISM(S): Mus musculus 
2006-04-18 | E-GEOD-4680 | biostudies-arrayexpress
ProteomicsAcute synthesis of CPEB is required for plasticity of visual avoidance behavior in Xenopus
Neural plasticity requires protein synthesis, but the identity of newly synthesized proteins generated in response to plasticity-inducing stimuli remains unclear. We used in vivo bio-orthogonal noncanonical amino acid tagging (BONCAT) with the methionine analog azidohomoalanine (AHA) combined with t...
ORGANISM(S): Xenopus Laevis (ncbitaxon:8355) 
2018-01-11 | MSV000081914 | MassIVE
UnknownNeural Plasticity in Multiple Sclerosis: The Functional and Molecular Background.
Not available
S-EPMC4503575 | biostudies-literature
UnknownTraining-Specific Neural Plasticity in Spinal Reflexes after Incomplete Spinal Cord Injury.
Not available
S-EPMC5048024 | biostudies-literature
UnknownReversing pathological neural activity using targeted plasticity.
Not available
S-EPMC3295231 | biostudies-literature
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