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TranscriptomicsThe miRNA pathway controls rapid changes in activity-dependent synaptic structure at the Drosophila melanogaster neuromuscular junction (miRNA array)
It is widely accepted that long-term changes in synapse structure and function are mediated by rapid activity-dependent gene transcription and new protein synthesis. A growing amount of evidence suggests that the microRNA (miRNA) pathway plays an important role in coordinating these processes. Despi...
ORGANISM(S): Drosophila melanogaster 
2013-02-01 | E-GEOD-43943 | biostudies-arrayexpress
TranscriptomicsThe miRNA pathway controls rapid changes in activity-dependent synaptic structure at the Drosophila melanogaster neuromuscular junction (RT-PCR)
It is widely accepted that long-term changes in synapse structure and function are mediated by rapid activity-dependent gene transcription and new protein synthesis. A growing amount of evidence suggests that the microRNA (miRNA) pathway plays an important role in coordinating these processes. Despi...
ORGANISM(S): Drosophila melanogaster 
2013-02-01 | E-GEOD-43944 | biostudies-arrayexpress
GenomicsProtein local synthesis at synapse is required for neuromuscular transmission
Protein local synthesis at synapse is required for neuromuscular transmission
PRJNA998037 | ENA
TranscriptomicsFiber and NMJ / synaptic gene expression comparisons in rat extraocular muscle (EOM) and tibialis anterior (TA) muscle.
Purpose: To examine and characterize the expression profile of genes expressed at the neuromuscular junctions (NMJs) of extraocular muscles (EOMs) in comparison to the NMJs of tibialis anterior muscle (TA). Methods: Adult rat rectus EOMs and TAs were dissected, flash-frozen, serially sectioned and ...
ORGANISM(S): Rattus norvegicus 
2010-04-28 | E-GEOD-15737 | biostudies-arrayexpress
TranscriptomicsThe miRNA pathway controls rapid changes in activity-dependent synaptic structure at the Drosophila melanogaster neuromuscular junction
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Drosophila melanogaster 
2013-02-01 | E-GEOD-43945 | biostudies-arrayexpress
OtherProtein local synthesis at synapse is required for neuromuscular transmission
To profile the local translatome at the neuromuscular junction during various developmental stages We conducted RNA sequencing of synapse-enriched regions in the mouse diaphragms of both cre- and cre+ mice to investigate the local translatome at motor neuron terminals
ORGANISM(S): Mus musculus 
2024-08-26 | GSE238144 | GEO
TranscriptomicsTranscriptome analysis of neuromuscular junction during degeneration and regeneration of axon terminal
The neuromuscular junction (NMJ) is a specialized tripartite synapse composed of the motor axon terminal, covered by perisynaptic Schwann cells (PSCs), and the muscle fibre, separated by a basal lamina. It is exposed to different kind of injures such as mechanical traumas, pathogens including neurot...
ORGANISM(S): Mus musculus 
2017-05-30 | E-MTAB-5730 | biostudies-arrayexpress
TranscriptomicsA Dach2-Hdac9-Myog-Gdf5 signaling system regulates regeneration of neuromuscular synapses
Muscle denervation due to injury, disease or aging results in impaired motor function. Restoring neuromuscular communication requires axonal regrowth and regeneration of neuromuscular synapses. Muscle activity inhibits neuromuscular synapse regeneration. The mechanism by which muscle activity regu...
ORGANISM(S): Mus musculus 
2015-10-29 | E-GEOD-58669 | biostudies-arrayexpress
UnknownMHCI promotes developmental synapse elimination and aging-related synapse loss at the vertebrate neuromuscular junction.
Not available
S-EPMC5813483 | biostudies-literature
ProteomicsPhosphoproteomics of MuSK Signaling
The development of the neuromuscular synapse depends on signaling processes which involve protein phosphorylation as a crucial regulatory event. The receptor tyrosine kinase MuSK is the key signaling molecule at the neuromuscular synapse whose activity is required for the formation of a mature and f...
ORGANISM(S): Mus musculus (Mouse) 
2014-06-05 | PXD000558 | Pride
Phospho Musk Mouse Neuromuscular synapse 
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