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MetabolomicsSCP4-STK35/PDIK1L complex is a dual phospho-catalytic signaling dependency in acute myeloid leukemia
Acute myeloid leukemia (AML) cells rely on phospho-signaling pathways to gain unlimited proliferation potential. Here, we used domain-focused CRISPR screening to identify the nuclear phosphatase SCP4 as a dependency in AML, yet this enzyme is dispensable in normal hematopoietic progenitor cells. Usi...
2025-05-29 | MTBLS3707 | MetaboLights
MetabolomicsLipidCreator workbench to probe the lipidomic landscape - Platelet isolation and stimulation, Targeted Phospho and Glycerolipid Profiling

Here we present LipidCreator, a software that fully supports targeted lipidomics assay development. LipidCreator offers a comprehensive framework to compute MS/MS fragment masses for over 60 lipid classes. LipidCreator provides all functionalities needed to define fragments, manage stable isotope...

2020-04-15 | MTBLS1369 | MetaboLights
MetabolomicsIdentifying metabolite changes in human islets treated with Phospho-BAD mimicry and Inflammatory cytokines
Not available
ORGANISM(S): Homo sapiens 
ST001953 | MetabolomicsWorkbench
ProteomicsPhospho enrichement in exponential and starvation condition
Phospho enrichement in exponential and starvation condition
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2026-06-20 | PXD059338 | Pride
Phospho enrichement 
ProteomicsPhosphorylation of Asc1p and Asc1p-dependent phospho-proteome
Phosphorylation of Asc1p and Asc1p-dependent phospho-proteome We determined 1) the phosphorylation sites within the Asc1 protein purified from Saccharomyces cerevisiae via its Strep-tag and 2) the Asc1p-dependent phospho-proteome. 1) Phospho-sites within tryptic peptides of Asc1p were identified usi...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2016-12-13 | PXD003031 | Pride
Lc-msms Asc1p Rack1 Silac Signal transduction Phosphorylation Saccharomyces cerevisiae Translation 
GenomicsiCLIP Analysis of WT, phospho-defective, and phospho-mimicking mutants of mouse Nucleolin in iKras PDAC cells
iCLIP Analysis of WT, phospho-defective, and phospho-mimicking mutants of mouse Nucleolin in iKras PDAC cells
PRJEB58806 | ENA
GenomicsPhospho-RNA sequencing with CircAID-p-seq
Phospho-RNA sequencing with CircAID-p-seq
PRJNA731473 | ENA
ProteomicsTransitions in the proteome and phospho-proteome during Xenopus laevis development.
Vertebrate development from an egg to a complex multi-tissue million-cell organism is supported by multiple phases of genome-scale remodeling of the repertoire of proteins and their post-translational modifications, yet so far we know little about these phases. In this paper we present comprehensive...
ORGANISM(S): Xenopus laevis (African clawed frog) 
2025-07-14 | PXD060481 | Pride
Tmt Development Eclipse Lumos Xenopus laevis 
ProteomicsSpatial-proteomics reveals phospho-signaling dynamics at subcellular resolution
Dynamic change in subcellular localization of signaling proteins is a general concept that eukaryotic cells evolved for responding and elicit a coordinated response to stimuli. Mass spectrometry (MS)-based proteomics in combination with subcellular fractionation can provide comprehensive maps of spa...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2021-11-18 | PXD023690 | Pride
Dia Spatio-temporal dynamics Proteomics Phosphoproteomics 
ProteomicsPhospho-proteome of obese mice brains
This study aims to investigate changes in phospho-proteomic levels of mice brain. The focus of the study is the phospho-proteome because phoshorylation is one of the key post-translational modification, which regulates many biological processes. In particular we wanted to inspect the effects of two ...
ORGANISM(S): Mus musculus (Mouse) 
2018-06-10 | PXD005815 | Pride
Obesity Diet Cns development Mice brains Phospho-proteome 
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