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MicroRNA microarray profiling analysis was performed on human gastric cancer HGC cells after RACK1 silenced or not
ORGANISM(S): Homo sapiens 
Fighting viral infections is hampered by the scarcity of viral targets and their variability resulting in development of resistance. Viruses depend on cellular molecules for their life cycle, which are attractive alternative targets, provided that they are dispensable for normal cell functions. Usin...
ORGANISM(S): Homo sapiens 
MicroRNA microarray profiling analysis was performed on human gastric cancer AGS cells after RACK1 silenced or not
ORGANISM(S): Homo sapiens 
Receptor for Activated C kinase 1 (RACK1) is a scaffold protein that has been found in association with several signaling complexes, and with the 40S subunit of the ribosome. Data presented here allowed a proteomic characterization of the interactome of RACK1 in drosophila S2 cells. We carried out L...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2017-05-29 | PXD002965 | Pride
MicroRNAs (miRNAs) regulate different aspects of plant development by post-transcriptional regulation of target genes. In Arabidopsis, DICER-LIKE 1 (DCL1) processes miRNA precursors (pri-miRNAs) to miRNA duplexes, which associate with ARGONAUTE 1 (AGO1). AGO1 together with the miRNA guide strand bin...
ORGANISM(S): Arabidopsis thaliana 
Dengue virus (DENV), a re-emerging virus transmitted by Aedes mosquitoes, causes severe pathogenesis in humans. No effective treatment is available against this virus. We recently identified the scaffold protein RACK1 as a component of the DENV replication complex, a macromolecular complex essential...
ORGANISM(S): Homo sapiens (Human) 
2022-02-04 | PXD030765 | Pride
This study investigates protein complexes associated with RacK1 under conditions of mTOR inhibition. Wild-type HeLa cells were treated with the mTOR inhibitor Torin1, followed by immunoprecipitation using a RacK1-specific antibody to enrich RacK1-associated protein complexes. The immunoprecipitates ...
ORGANISM(S): Homo sapiens (Human) 
2026-02-21 | PXD073592 | Pride
Anorectal malformation (ARM), a common congenital anomaly of the digestive tract, is a result of insufficient elongation of the urorectal septum. The cytoplasmic protein Receptor of Activated C-Kinase 1 (Rack1) is involved in embryonic neural development; however, its role in embryonic digestive tra...
ORGANISM(S): Rattus norvegicus 
Splenic FO B and MZ B cells from Rack1(f/f) and Rack1(f/f CD19-Cre) mice were sorted and subjected to bulk RNA-seq
RACK1 maintains mouse hematopoietic stem cells by directly binding to and stabilizing LDB1
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