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ProteomicsProteomic analysis of RacK1 immunoprecipitates from Torin1-treated wild-type HeLa cells
This study investigates protein complexes associated with RacK1 under conditions of mTOR inhibition. Wild-type HeLa cells were treated with the mTOR inhibitor Torin1, followed by immunoprecipitation using a RacK1-specific antibody to enrich RacK1-associated protein complexes. The immunoprecipitates ...
ORGANISM(S): Homo sapiens (Human) 
2026-02-21 | PXD073592 | Pride
Torin1 Immunoprecipitation Rack1 Lc–ms/ms 
GenomicsmiCLIP, RNA-Seq in HEK293E cells treated with Torin1
miCLIP, RNA-Seq in HEK293E cells treated with Torin1
PRJNA639865 | ENA
TranscriptomicsComparison of transcriptomes between DMSO-5uM and Torin1-5uM treated mouse cumulus-oocyte complexes cultured in vitro for 14h
We sought to identify the potential specific roles of the MTOR signalling in cumulus cells by comparing the transcriptomes of the Control (treated with the DMSO vehicle) and MTOR-specific inhibitor Torin 1(5uM)-treated cumulus-oocyte complexes that were cultured for 16 hours. We compared the transcr...
ORGANISM(S): Mus musculus 
2016-08-01 | E-GEOD-79862 | biostudies-arrayexpress
GenomicsJ774.1 mouse macrophage-like cell line: Control vs. IR or TAM or Torin1
J774.1 mouse macrophage-like cell line: Control vs. IR or TAM or Torin1
PRJNA702072 | ENA
TranscriptomicsmiCLIP, RNA-Seq in HEK293E cells treated with Torin1
m6A RNA methylation and transcriptome profiling in were performed HEK293E cells following treatment with Torin1
ORGANISM(S): Homo sapiens 
2021-06-16 | GSE152633 | GEO
UnknownTorin1-mediated TOR kinase inhibition reduces Wee1 levels and advances mitotic commitment in fission yeast and HeLa cells.
Not available
S-EPMC3953821 | biostudies-literature
UnknownLifespan extension without fertility reduction following dietary addition of the autophagy activator Torin1 in Drosophila melanogaster.
Not available
S-EPMC5766080 | biostudies-literature
TranscriptomicsJ774.1 mouse macrophage-like cell line: Control vs. IR or TAM or Torin1
Transcriptional profiling of J774.1 cells comparing control (DMSO treatment) with IR or TAM or Torin1 treated cells.
ORGANISM(S): Mus musculus 
2022-02-15 | GSE166821 | GEO
Transcriptomicswild-type and gaf1 mutant cells treated with Torin1 or with a combination of caffeine/rapamycin
Target of Rapamycin Complex 1 (TORC1) signaling promotes growth and ageing. Inhibition of TORC1 leads to a down-regulation of factors that stimulate protein translation, which in turn contributes to longevity. TORC1-dependent post-transcriptional regulation of protein translation has been well studi...
ORGANISM(S): Schizosaccharomyces pombe 
2020-03-02 | E-MTAB-8569 | biostudies-arrayexpress
GenomicsEffect of feeding on gene expression in HEK-293E cells either treated with Torin1 or not.
Effect of feeding on gene expression in HEK-293E cells either treated with Torin1 or not.
PRJNA1141525 | ENA
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