Norepinephrine (NE) and acetylcholine (ACh) are important neurotransmitters of sympathetic and parasympathetic nerves, which play antagonistic roles in regulating different islet hormones secretion. Phosphorylation is reported as a critical post-translational modification participates in neural regu...
Purpose: Gut microbiota-brain axis serves as an emerging pathway affecting brain function. Hindgut has a higher proportion of microbes than foregut, however whether alteration in hindgut microbiota is related to brain functional change remains unclear. The present study used antibiotics to modulate ...
Excitatory-inhibitory (E-I) balance results from a complex interplay between glutamatergic and GABAergic neurons, and E-I imbalance has been proposed to contribute to many neurological diseases. We have created the first excitatory (S-2-methyglutamate or S-2MeGlu) and inhibitory (R-4-aminopentanoate...