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ProteomicsNeutralization mechanism of a HipA-like toxin targeting isoleucyl-tRNA synthetase
HipAB is a type II toxin-antitoxin (TA) system that targets and inactivates specific aminoacyl-tRNA synthetases in response to various stresses. While the molecular targets and neutralization mechanisms of several HipAB-like TA systems have been well characterized, their structural and functional di...
ORGANISM(S): Escherichia Coli K-12 
PXD062828 |
ProteomicsA simplified perchloric acid workflow with neutralization (PCA N) for democratizing deep plasma proteomics at population scale - Submission01
Large scale plasma proteomics studies offer tremendous potential for biomarker discovery but face significant challenges in balancing analytical depth, throughput and cost effectiveness. We present an optimized perchloric acid based workflow with neutralization – PCA N – that addresses these limitat...
ORGANISM(S): Homo sapiens (Human) 
2025-09-30 | PXD062274 | Pride
Lc-msms Plasma 
ProteomicsA simplified perchloric acid workflow with neutralization (PCA N) for democratizing deep plasma proteomics at population scale - Submission02
Large scale plasma proteomics studies offer tremendous potential for biomarker discovery but face significant challenges in balancing analytical depth, throughput and cost effectiveness. We present an optimized perchloric acid based workflow with neutralization – PCA N – that addresses these limitat...
ORGANISM(S): Homo sapiens (Human) 
2025-09-30 | PXD062275 | Pride
Lc-msms Plasma 
ProteomicsA simplified perchloric acid workflow with neutralization (PCA N) for democratizing deep plasma proteomics at population scale - Submission 3
Large scale plasma proteomics studies offer tremendous potential for biomarker discovery but face significant challenges in balancing analytical depth, throughput and cost effectiveness. We present an optimized perchloric acid based workflow with neutralization – PCA N – that addresses these limitat...
ORGANISM(S): Homo sapiens (Human) 
2025-09-30 | PXD062313 | Pride
Lc-msms Plasma 
GenomicsOncostatin M neutralization in E. coli pneumonia
Oncostatin M neutralization in E. coli pneumonia
PRJNA649240 | ENA
GenomicsIL-13 neutralization effect on COVID-19 severity
IL-13 neutralization effect on COVID-19 severity
PRJNA748702 | ENA
ProteomicsDefining neutralization and allostery by antibodies against COVID-19 variants
This project is aimed at characterizing the interactions of SARS-CoV-2 Spike protein and its variants with multiple full-length antibodies and monitoring the accompanying conformational dynamics. Different categories of antibodies are tested that recognize different domains of the Spike protein. The...
ORGANISM(S): Homo sapiens (Human) 
2023-10-09 | PXD043818 | Pride
Antibody Epitope-paratope mapping Sars-cov-2 Hdxms Neutralization Md simulations Variants of concern Spike protein 
GenomicsAcyl-coA Binding Protein neutralization improves cancer immunosurveillance
Acyl-coA Binding Protein neutralization improves cancer immunosurveillance
PRJNA1011354 | ENA
GenomicsNeutralization of Acyl-CoA Binding Protein Confers Autophagy-Dependent Organ Protection
Neutralization of Acyl-CoA Binding Protein Confers Autophagy-Dependent Organ Protection
PRJNA800343 | ENA
TranscriptomicsIL-13 neutralization effect on COVID-19 severity
We investigated the effect of IL-13 neutralization on COVID-19 disease progression in mice.
ORGANISM(S): Mus musculus 
2021-07-23 | GSE180557 | GEO
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