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UnknownSwitching to less expensive blindness drug could save medicare part B $18 billion over a ten-year period.
Not available
S-EPMC4137040 | biostudies-literature
GenomicNIA Long Life Family Study (LLFS)

The Long Life Family Study (LLFS) is an international collaborative study of the genetics and familial components of exceptional survival, longevity, and healthy aging. Families were recruited through elderly probands (generally in their 90s) who self-reported on the survival history of their par...

phs000397 | dbGaP
TranscriptomicsTranscription profiling of Arabidopsis mutants mpk4 and ctr1
Arabidopsis MPK4 is involved in the control of antagonism between salicylic acid (SA) and ethylene (ET)/jasmonic acid (JA) pathways in the plant innate immune system as a repressor of the SA pathway, but an activator of the ET/JA pathway. Here we and use comparative microarray analysis of ctr1, ctr1...
ORGANISM(S): Arabidopsis thaliana 
2005-08-01 | E-MEXP-174 | biostudies-arrayexpress
GenomicsNational Institute on Aging (NIA) Long Life Family Study (LLFS)

The Long Life Family Study (LLFS) is an international collaborative study of the genetics and familial components of exceptional survival, longevity, and healthy aging. Families were recruited through elderly probands (generally in their 90s) who self-reported on the survival history of their par...

phs000397.v1.p1 | EGA
TranscriptomicsTranscription profiling of Arabidopsis wild type, 35S:mks1 and mpk4 plants
In plants, MAPKs are implicated in signalling cascades regulating immediate as well as systemic responses to pathogens. Arabidopsis MAP kinase 4 (MPK4) negatively regulates systemic acquired resistance (SAR) accompanied by the expression of pathogenesis-related (PR) genes. MPK4 interacts with and ph...
ORGANISM(S): Arabidopsis thaliana 
2005-09-01 | E-MEXP-173 | biostudies-arrayexpress
ProteomicsSAINT_3727_JQ1_APMS_endoK562_P82_VS17_28AUG2018
This submission contains the mass spectrometry files for the manuscript by Lambert, Picaud et al. that describes the characterization of interactome changes induced by JQ1 on the BET proteins. This submission contains 16 files associated with endogenous IP-MS analysis of BRD2, BRD3 and BRD4 (IgG was...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-08-28 | MSV000082859 | MassIVE
ProteomicsLambert_BRD_SAINT2307_JQ1_APMS_time_course_TripleTOF_P82_VS5
This submission contains the mass spectrometry files for the manuscript by Lambert, Picaud et al. that describes the characterization of interactome changes induced by JQ1 on the BET proteins. More precisely, files used in the SAINT express task 2307 are in this dataset. The AP-MS experiments involv...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-04-25 | MSV000081006 | MassIVE
ProteomicsA truncated MRE11 form induced by SPRTN is deficient in DNA repair and radiosensitises cancer cells
he human MRE11/RAD50/NBS1 (MRN) complex plays a crucial role in sensing and repairing DNA DSB. MRE11 possesses 3’-5’ exonuclease and endonuclease activity and forms the core of the multifunctional MRN complex. We previously identified a C-terminally truncated form of MRE11 (TR-MRE11) associated with...
ORGANISM(S): Homo sapiens (Human) 
2021-02-23 | PXD017964 | Pride
C-terminal truncation Mre11 cleavage Mre11 Dna repair Sprtn 
ProteomicsSAINT_3726_JQ1_APMS_endoHEK293_P82_VS16_28AUG2018
This submission contains the mass spectrometry files for the manuscript by Lambert, Picaud et al. that describes the characterization of interactome changes induced by JQ1 on the BET proteins. This submission contains 16 files associated with endogenous IP-MS analysis of BRD2, BRD3 and BRD4 (IgG was...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-08-28 | MSV000082857 | MassIVE
UnknownRecombination and transposition drive genomic structural variation potentially impacting life history traits in a host-generalist fungal plant pathogen.
Not available
S-EPMC12036203 | biostudies-literature
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