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UnknownMulticenter study to assess the use of BL-DetecTool for the detection of CTX-M-type ESBLs and carbapenemases directly from clinical specimens.
Not available
S-EPMC10935652 | biostudies-literature
ProteomicsDiscovery from in-depth molecular analyses of giant viruses: Haptophyte-infecting viruses change the genome condensing proteins of dinoflagellates
Giant viruses are extraordinary members of the virosphere due to their structural complexity and high diversity in gene content. Haptophytes are ecologically important primary producers in the ocean, and all known viruses that infect haptophytes are giant viruses. Our in-depth electron microscopic, ...
ORGANISM(S): Prymnesium kappa virus 
2025-02-21 | PXD060762 | Pride
Haptolina ericina virus Giant viruses Haptophytes Prymnesium kappa virus 
ProteomicsStructure of NO16, a marine non-tailed vibriophage with an unusual symmetry-mismatched vertex arrangement
Non-tailed phages remain underexplored in marine environments, as tailed phages have long dominated sequence and culture collections. Yet recent surveys suggest that non-tailed phages may be more abundant and have distinct impacts on microbial mortality and gene transfer. Here, we solve the structur...
ORGANISM(S): Elsinorevirus NO16 Vibrio anguillarum 
2026-08-07 | PXD070644 | Pride
Vibriophage Marine virus 
MetabolomicsPeripheral modulation of antidepressant targets MAO-B and GABAAR by harmol induces mitohormesis and delays aging in preclinical models
Reversible and sub-lethal stresses to the mitochondria elicit a program of compensatory responses that ultimately improve mitochondrial function, a conserved anti-aging mechanism termed mitohormesis. Here, we show that harmol, a member of the beta-carbolines family with anti-depressant properties, i...
2023-05-26 | MTBLS7533 | MetaboLights
ProteomicsThe serum of COVID-19 asymptomatic patients in circulating angiogenic cells ex-vivo
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has provoked, up to date, more than 5 million deaths worldwide. While asymptomatic individuals are responsible of many potential transmissions, the difficulty to identify and isolate them at the high peak of infection constitut...
ORGANISM(S): Homo sapiens (Human) 
2022-05-20 | PXD030860 | Pride
Covid-19 Asymptomatic Proteomics Endothelial dysfunction Circulating angiogenic cells Sars-cov-2 Endothelial progenitor cells 
MetabolomicsPathogenic NLRP3 mutants form constitutively active inflammasomes resulting in immune-metabolic limitation of IL-1β production

BACKGROUND: Cryopyrin-Associated Periodic Syndrome (CAPS) is an autoinflammatory condition consequence of monoallelic variants in the NLRP3 gene that exacerbate IL-1β production. These variants are gain-of-function, but the exact regulatory mechanism of the NLRP3 CAPS-inflammasom...

2024-01-09 | MTBLS7872 | MetaboLights
UnknownVariability among TSH Measurements Can Be Reduced by Combining a Glycoengineered Calibrator to Epitope-Defined Immunoassays.
Not available
S-EPMC5465719 | biostudies-literature
UnknownGender differences in transcriptional signature of developing rat testes and ovaries following embryonic exposure to 2,3,7,8-TCDD.
Not available
S-EPMC3392256 | biostudies-literature
UnknownFecal immunochemical test accuracy in average-risk colorectal cancer screening.
Not available
S-EPMC3921527 | biostudies-literature
TranscriptomicsTranscription profiling of human cell lines treated with cytochalasin D and nocodazole with the aim of characterising tetraploid clones
During the oncogenic process, tetraploidy is a candidate intermediate stage leading from diploidy to aneuploidy. The aim of our experiment was to establish tetraploid clones and to characterize their transcriptome.
ORGANISM(S): Homo sapiens 
2006-03-01 | E-TABM-70 | biostudies-arrayexpress
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