Sort   by:  
 Page size 
TranscriptomicsTranscription profiling of human epidermal keratinocytes (NHEK) from neonatal foreskin treated with IL20 subfamily cytokines vs. controls suggests potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis
Normal human epidermal keratinocytes (NHEK) from neonatal foreskin were cultured in serum-free EpiLife medium with human KC growth supplement (0.2% bovine pituitary extract (v/v), 5ug bovine insulin, 5ug/ml bovine transferrin, 0.5ng/ml human EGF, and 0.18 ug/ml hydrocortisone) from Cascade Biologics...
ORGANISM(S): Homo sapiens 
2007-11-01 | E-GEOD-7216 | biostudies-arrayexpress
TranscriptomicsGenome-wide expression erofiling of an in vitro model for studying esophageal epithelial differentiation
We used RNA sequencing to identify differentially expressed genes during esophageal epithelial differentiation and in the presence of interleukin 13 using an air-liquid interface culture system. RNA sequencing was performed on a human esophageal epithelial cell line (EPC2-hTERT) grown submerged (day...
ORGANISM(S): Homo sapiens 
2015-02-01 | E-GEOD-65335 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Drosophila cell lines S3, Kc and S3
Background: We would like to use Drosophila cell lines to investigate the transcriptional responses to Nitric Oxide donors and inhibitors. As a pilot to this we would like to compare the transcriptional profile of 3 cell lines we are using in our lab (S3, Kc and S3). This study is being done in para...
ORGANISM(S): Drosophila melanogaster 
2004-05-07 | E-FLYC-4 | biostudies-arrayexpress
ProteomicsA general multipronged activation approach for natural product discovery in Actinomycetes 54 actinobacterial strains with genetic and cultivation based activation
LC-MS/MS fermentation extract collection of 54 diverse and non-domesticated actinobacterial strains interrogated with a one-step integrase-mediated genetic- and cultivation-based approach to perturb and activate metabolite production in actinobacteria that has significantly increased accessible meta...
ORGANISM(S): Streptomyces Viridochromogenes (ncbitaxon:1938) Streptomyces Abikoensis (ncbitaxon:97398) Thermoactinomyces Vulgaris (ncbitaxon:2026) Streptomyces Albogriseolus (ncbitaxon:1887) Streptomyces Sampsonii (ncbitaxon:42239) Streptomyces Ardesiacus Streptomyces Fradiae (ncbitaxon:1906) Streptomyces Filipinensis (ncbitaxon:66887) Streptomyces Niveiscabiei (ncbitaxon:164115) Streptomyces Odonnellii (ncbitaxon:1417980) Streptomyces Anandii (ncbitaxon:285454) Streptomyces Thermocarboxydus (ncbitaxon:59299) Streptomyces Flaveolus (ncbitaxon:67297) Streptomyces Albofaciens (ncbitaxon:66866) Micromonospora Maris Streptomyces Luridiscabiei (ncbitaxon:164114) Streptomyces Lavendulae (ncbitaxon:1914) Streptomyces (ncbitaxon:1883) Spirillospora Tritici Streptomyces Kronopolitis (ncbitaxon:1612435) Streptomyces Niveoruber (ncbitaxon:68243) Streptomyces Cyaneochromogenes Streptomyces Lunaelactis (ncbitaxon:1535768) Streptomyces Hirsutus (ncbitaxon:35620) Streptomyces Jeddahensis (ncbitaxon:1716141) Streptomyces Tendae Strain Atcc 19812 Micromonospora Oryzae (ncbitaxon:1530046) Streptomyces Nigrescens (ncbitaxon:1920) Streptomyces Durhamensis (ncbitaxon:68194) Streptomyces Variabilis (ncbitaxon:67372) Micromonospora Aurantiaca (ncbitaxon:47850) Streptomyces Tendae (ncbitaxon:1932) Micromonospora Maritima (ncbitaxon:986711) Streptomyces Globisporus (ncbitaxon:1908) Dactylosporangium Solaniradicis (ncbitaxon:1758122) 
2023-06-22 | MSV000092237 | MassIVE
UnknownPeroxisome Proliferator-Activated Receptor γ Level Contributes to Structural Integrity and Component Production of Elastic Fibers in the Aorta.
Not available
S-EPMC4865434 | biostudies-literature
TranscriptomicsIntegrative responses to IL-17 and TNF-α in human keratinocytes account for key inflammatory pathogenic circuits in psoriasis
We sought to provide a comprehensive evaluation of the effects of TNF-α and IL-17 on the keratinocyte gene profile in order to identify genes that might be co-regulated by these cytokines. We then sought to determine how genes that were synergistically activated by both cytokines relate to the psori...
ORGANISM(S): Homo sapiens 
2010-11-24 | E-GEOD-24767 | biostudies-arrayexpress
TranscriptomicsRB Dysfunction in Pancreatic Cancer Enables TGF-beta to Promote Proliferation
Pooled KRC (LSL-KrasG12D; Rb1L/L; Pdx1-Cre: oncogenic Kras and deleted Rb1 in the pancreas) cells derived from 2 month old mice were compared to pooled KC (LSL-KrasG12D; Pdx1-Cre: oncogenic Kras in the pancreas) cells derived from 8 month old mice.
ORGANISM(S): Mus musculus 
2014-02-09 | E-MEXP-3988 | biostudies-arrayexpress
UnknownAntibiotic utilisation and resistance over the first decade of nationally funded antimicrobial stewardship programmes in Singapore acute-care hospitals.
Not available
S-EPMC10464409 | biostudies-literature
TranscriptomicsMouse Sirt6-/- TNF-alpha timecourse
We completed genome-wide microarray analysis in Sirt6 knockout (ko) mouse embryonic fibroblasts (MEFs) and control wildtype (wt) MEFs. Prior to RNA extraction, MEFs were treated with TNF-alpha (10 ng/ml) for the indicated times. Total RNA was extracted with TRIzol (Invitrogen) and amplified with Amb...
ORGANISM(S): Mus musculus 
2010-06-24 | E-GEOD-13207 | biostudies-arrayexpress
UnknownReciprocal regulation of 11β-hydroxysteroid dehydrogenase 1 and glucocorticoid receptor expression by dexamethasone inhibits human coronary artery smooth muscle cell proliferation in vitro.
Not available
S-EPMC2996480 | biostudies-literature
Sort   by:  
 Page size