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ProteomicsNascent glycoproteome reveal the suppressed expression of glycosylated LAMP2 in response to N-linked glycosylation inhibition
(1) Analysis of newly synthesized proteins under glycosylation inhibition (2) Analysis of newly synthesized glycoproteins during NGI-1 treatment
ORGANISM(S): Homo Sapiens 
PXD028212 |
ProteomicsTargeting conserved N-glycosylation eradicates SARS-CoV-2 variants infection
Despite the clinical success of anti-spike vaccines, the effectiveness of neutralizing antibodies and vaccines by rapidly spreading SARS-CoV-2 variants has been compromised. Viruses can hijack the glycosylation machinery of host cells to shield themselves from the host’s immune response and attenuat...
ORGANISM(S): Homo sapiens (Human) 
2021-07-30 | PXD026852 | Pride
Sars-cov-2 variant Ngi-1 Stt3a Deglycosylation Adc 
TranscriptomicsRNA sequencing/Gene expression studies of N-glycosylation inhibitors in diffuse lymphoma
We determined that N-linked glycosylation p[lays a role in oncogenic signaling in diffuse lymphoma. We sought to obtain gene expression data and gene signatures in diffuse lymphoma cells by examining changes in gene expression by RNA seq following treatment with the N-linked glycosylation inhibitor ...
ORGANISM(S): Homo sapiens 
2022-09-06 | GSE212337 | GEO
UnknownOligosaccharyltransferase Inhibition Reduces Receptor Tyrosine Kinase Activation and Enhances Glioma Radiosensitivity.
Not available
S-EPMC6314911 | biostudies-literature
UnknownNascent Glycoproteome Reveals That N-Linked Glycosylation Inhibitor-1 Suppresses Expression of Glycosylated Lysosome-Associated Membrane Protein-2.
Not available
S-EPMC9092021 | biostudies-literature
UnknownA Small-Molecule Oligosaccharyltransferase Inhibitor with Pan-flaviviral Activity.
Not available
S-EPMC5734657 | biostudies-literature
UnknownApplication of next-generation imaging in biochemically recurrent prostate cancer.
Not available
S-EPMC11096127 | biostudies-literature
ProteomicsTargeting conserved N-glycosylation eradicates SARS-CoV-2 variants infection
To assess the binding ability of glycosylated or deglycosylated spike with ACE2, we performed flow cytometry, ELISA, and BioLayer Interferometry methods. Viral entry ability was determined by luciferase intensity, immunoblotting, and immunofluorescence assay. A genome-wide association study (GWAS) w...
ORGANISM(S): Human 
2021-06-23 | MSV000087686 | MassIVE
UnknownEditing N-Glycan Site Occupancy with Small-Molecule Oligosaccharyltransferase Inhibitors.
Not available
S-EPMC6337728 | biostudies-literature
UnknownOligosaccharyltransferase inhibition induces senescence in RTK-driven tumor cells.
Not available
S-EPMC5393272 | biostudies-literature
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