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Transcriptomicsp53- repressed miRNAs are involved with E2F in a feed forward loop promoting proliferation
There is a distinctive miRNA expression profile between early (young) and replicative senescence (old). We observed a cluster of miRNAs that were repressed upon senescence in both MRC-5 and WI-38 fibroblast cells. miRNAs profiling in young and senescence human emryonic fibroblasts (MRC-5 and WI-38)
ORGANISM(S): Homo sapiens 
2010-05-19 | E-GEOD-12821 | biostudies-arrayexpress
UnknownConquering hypertension in Vietnam: 12- month follow up results from a cluster-randomised controlled trial.
Not available
S-EPMC11263625 | biostudies-literature
UnknownCombination of Hotspot Mutations With Methylation and Fragmentomic Profiles to Enhance Multi-Cancer Early Detection.
Not available
S-EPMC11695824 | biostudies-literature
TranscriptomicsPaired non-cancerous and cancerous miRNA expression of esophageal adenocarcinoma and squamous cell carcinoma patients
Identifying biomarkers predictive for early esophageal cancer detection is critical considering the dismal survival rates. We investigated the involvement of microRNAs (miRNAs), their utility as biomarkers, and their association with survival in esophageal cancer, including Barrett’s associated and...
ORGANISM(S): Homo sapiens 
2010-07-09 | E-GEOD-13937 | biostudies-arrayexpress
Transcriptomicsp53-repressed miRNAs are Involved with E2F in a Feed Forward Loop Promoting Proliferation
Analysis of miRNA expression in human breast cancer samples with Agilent's miRNA arrays. These samples are part of a study where we have investigated the mammalian cell proliferation control network consisting of transcription regulators, E2F and p53, their targets, and a family of 14 microRNAs. We ...
ORGANISM(S): Homo sapiens 
2008-09-22 | E-GEOD-12848 | biostudies-arrayexpress
Transcriptomicsp53-repressed miRNAs are Involved with E2F in a Feed Forward Loop Promoting Proliferation
miRNA expression profiles of WI38 primary human fibroblasts with an active or inactive p53. Cells were compared under normal untreated conditions (young and proliferating cells), after DNA damage with Doxorubicin, and upon entry into replicative senescence. Keywords: miRNA, WI-38, p53, GSE56, Senes...
ORGANISM(S): Homo sapiens 
2010-05-19 | E-GEOD-12450 | biostudies-arrayexpress
UnknownA global metagenomic map of urban microbiomes and antimicrobial resistance.
Not available
S-EPMC8238498 | biostudies-literature
UnknownCAMP: a modular metagenomics analysis system for integrated multistep data exploration.
Not available
S-EPMC12809600 | biostudies-literature
UnknownDeath following pulmonary complications of surgery before and during the SARS-CoV-2 pandemic.
Not available
S-EPMC10364875 | biostudies-literature
UnknownA prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts.
Not available
S-EPMC12056793 | biostudies-literature
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