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TranscriptomicsscRNAseq dataset from neuroblastomas tumoroids
Neuroblastoma (NB), a pediatric cancer arising from disrupted sympathetic neuron differentiation, exhibits marked heterogeneity and limited therapeutic options. To better understand its molecular circuitry dynamics, we applied CARDAMOM, a novel Gene Regulatory Network (GRN) inference framework to s...
ORGANISM(S): Homo sapiens 
2026-07-07 | E-MTAB-16741 | biostudies-arrayexpress
TranscriptomicsDichlorvos exposure results in large scale disruption of energy metabolism in the liver of the zebrafish, Danio rerio
Background: Exposure to dichlorvos (DDVP), an organophosphorus pesticide, is known to result in neurotoxicity as well as other metabolic perturbations. However, the molecular causes of DDVP toxicity are poorly understood, especially in cells other than neurons and muscle cells. To obtain a better un...
ORGANISM(S): Danio rerio 
2015-11-05 | E-GEOD-66257 | biostudies-arrayexpress
TranscriptomicsDistance Effect
Here we show that regions of the honeybee brain involved in visual processing and learning and memory show a genomic response to distance information. Using a method that separates effects of perceived distance from effects of actual distance flown, we found that individuals forced to shift from a s...
ORGANISM(S): Apis mellifera 
2011-03-05 | E-TABM-910 | biostudies-arrayexpress
TranscriptomicsIGR_U985_CLL_EGR2_GE_STUDY_OB
Chronic lymphocytic leukemia (CLL), the most frequent adult leukemia in western countries, is a clonal accumulation of mature B-lymphocytes and its natural history is yet unclear. By using sequencing and cellular biology approaches on a cohort of CLL patient samples, we show here that acquired CLL m...
ORGANISM(S): Mus musculus 
2014-06-18 | E-MTAB-1764 | biostudies-arrayexpress
TranscriptomicsTranscriptomic analysis reveals novel long non-coding RNAs critical for vertebrate development [Illumina]
Long non-coding RNAs (lncRNAs) have emerged as critical regulators of gene expression and chromatin modifications, with important functions in development and disease. Here we sought to identify and functionally characterize lncRNAs critical for vascular vertebrate development with significant conse...
ORGANISM(S): Homo sapiens 
2015-05-15 | E-GEOD-54966 | biostudies-arrayexpress
TranscriptomicsTranscriptomic analysis reveals novel long non-coding RNAs critical for vertebrate development [Affymetrix]
Long non-coding RNAs (lncRNAs) have emerged as critical regulators of gene expression and chromatin modifications, with important functions in development and disease. Here we sought to identify and functionally characterize lncRNAs critical for vascular vertebrate development with significant conse...
ORGANISM(S): Homo sapiens 
2015-05-15 | E-GEOD-54964 | biostudies-arrayexpress
TranscriptomicsTranscriptomic analysis reveals novel long non-coding RNAs critical for vertebrate development [RNA-Seq]
Long non-coding RNAs (lncRNAs) have emerged as critical regulators of gene expression and chromatin modifications, with important functions in development and disease. Here we sought to identify and functionally characterize lncRNAs critical for vascular vertebrate development with significant conse...
ORGANISM(S): Homo sapiens 
2015-05-15 | E-GEOD-54968 | biostudies-arrayexpress
TranscriptomicsPAO1-1037
Gene expression in biofilms of PAO1 with and without the presence of 20 ug/ml peptide 1037 was analysed using microarrays.
ORGANISM(S): Pseudomonas aeruginosa 
2012-04-19 | E-MTAB-962 | biostudies-arrayexpress
no omics definedTranscription profiling of maize to identify gene expression changes after chilling for 28 hours (acclimation phase)
The aim of this study was to identify alarm (fast) and acclimation phase (delayed) changes in the gene expression pattern in leaves of maize (CM 109 genotype) subjected to moderate chilling for 28 hours.
ORGANISM(S): Zea mays 
2009-11-01 | E-MEXP-1865 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of maize to identify gene expression changes after chilling for 4 hours (alarm phase)
This experiment evaluates quick (alarm) response to chilling in chilling-sensitive maize plants.
Maize inbred line cm109 were grown in optimal conditions until third leaf was fully developed.
At this stage plants were divided into three experimental variants: k0 - control plants, frozen
at...
ORGANISM(S): Zea mays 
2009-11-01 | E-MEXP-1875 | biostudies-arrayexpress
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