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ProteomicsHuman naive T-cell secretome, activated and non-activated
In vitro culture of 2 separate sets of naive human T cells (from 2 adult male donors), activated using CD3 and CD28 antibodies. Secretome collection at 48 hours after activation. The same cell cultures not activated and sampled at the exact same time served as 'not-activated control'.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-10-30 | MSV000086390 | MassIVE
ProteomicsRecombinant SWATH library for identification of low abundant human plasma proteins
Recombinant SWATH library for identification of low abundant human plasma proteins
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-11-04 | MSV000086411 | MassIVE
ProteomicsPHGDH Arginine Methylation by PRMT1 Promotes Serine Synthesis and Represents a Therapeutic Vulnerability in Hepatocellular Carcinoma
Serine synthesis is crucial for tumor growth and survival, but its regulatory mechanism in cancer remains elusive. Here, we found that R236 methylation of PHGDH promotes its activity and stimulates serine synthesis in hepatocellular carcinoma.
ORGANISM(S): Homo Sapiens 
PXD035061 |
ProteomicsPHGDH Arginine Methylation by PRMT1 Promotes Serine Synthesis and HCC Growth
Serine synthesis is crucial for tumor growth and survival, but its regulatory mechanism in cancer remains elusive. Phosphoglycerate dehydrogenase (PHGDH) is the first rate-limiting enzyme in serine biosynthesis pathway. Here, we analyzed immunoprecipitated PHGDH from human HEK293T cells by liquid ch...
ORGANISM(S): Homo Sapiens 
PXD035287 |
ProteomicsDisrupting metformin adaptation of hepatocellular carcinoma by targeting TOMM34/ATP5B axis
As a well-known anti-diabetic drug, metformin has been repurposed for cancer treatment, but drug resistance and tumor metastasis observed recently have challenged its further application. Here, we found that long-term metformin exposure led to metabolic adaptation of HCC cells, which was characteriz...
ORGANISM(S): Homo Sapiens 
PXD035365 |
UnknownAn initial report from the French SOT COVID Registry suggests high mortality due to COVID-19 in recipients of kidney transplants.
Not available
S-EPMC7444636 | biostudies-literature
UnknownAbsence of Mortality Differences Between the First and Second COVID-19 Waves in Kidney Transplant Recipients.
Not available
S-EPMC9489985 | biostudies-literature
UnknownClinical Utility of Biochemical Markers for the Prediction of COVID-19-Related Mortality in Kidney Transplant Recipients.
Not available
S-EPMC8264524 | biostudies-literature
UnknownCorticosteroids in patients hospitalized for COVID-19 pneumonia who require oxygen: observational comparative study using routine care data.
Not available
S-EPMC7722522 | biostudies-literature
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