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TranscriptomicsRemission in Polyarticular Juvenile Idiopathic Arthritis
Identify biomarkers to predict response to therapy in polyarticular juvenile idiopathic arthritis (JIA) using gene expression microarrays. 42 samples from 13 controls, 14 active patients, 9 patients in clinical remission with medication (CRM), and 6 patients in clinical remission without medication ...
ORGANISM(S): Homo sapiens 
2009-04-13 | E-GEOD-15645 | biostudies-arrayexpress
UnknownRandomized, Prospective Evaluation Comparing Intensity of Lymphodepletion Before Adoptive Transfer of Tumor-Infiltrating Lymphocytes for Patients With Metastatic Melanoma.
Not available
S-EPMC4981979 | biostudies-literature
ProteomicsDeciphering O-glycoprotease substrate preferences with O-Pair Search
O-glycoproteases are an emerging class of enzymes that selectively digest glycoproteins at positions decorated with specific O-linked glycans. O-glycoprotease substrates range from any O-glycoprotein (albeit with specific O-glycan modifications) to only glycoproteins harboring specific O-glycosylate...
ORGANISM(S): Homo sapiens (Human) 
2023-02-15 | PXD035775 | Pride
O-glycoproteomics Glycoproteins Cleavage Glycoproteomics Informatics O-pair search O-glycoprotease 
ProteomicsAmino acids essential for function in the Plant-Conserved and Class-Specific Regions of plant cellulose synthase
The Plant-Conserved Region (P-CR) and the Class-Specific Region (CSR) are two unique sequences inserted into the catalytic core of plant cellulose synthases. Either or both of these domains might promote assembly of the synthase complex. From structural studies of these domains, we have identified c...
ORGANISM(S): Arabidopsis Thaliana (ncbitaxon:3702) 
2022-07-12 | MSV000089874 | MassIVE
TranscriptomicsLocation-specific responses to thermal stress in larvae of the reef-building coral Montastraea faveolata
The potential to adapt to a changing climate depends in part upon the standing genetic variation present in wild populations. In corals, the dispersive larval phase is particularly vulnerable to the effects of environmental stress. Larval survival and response to stress during dispersal and settleme...
ORGANISM(S): Montastraea faveolata 
2010-06-23 | E-GEOD-19998 | biostudies-arrayexpress
ProteomicsInfluenza vaccination in the elderly boosts antibodies against conserved viral proteins and egg-produced glycans
Proteomic analysis of serum IgG antibody repertoire against influenza vaccine H1 (H1N1 A/California/7/2009) and H3 (H3N2 A/Texas/50/2012) in young, middle-aged, and elderly donors vaccinated with Fluzone 2013-14/14-15. Dataset consists of peak-response (days 21-28 post-vaccination) serum IgG samples...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000086108 | MassIVE
UnknownSources of Black Carbon Deposition to the Himalayan Glaciers in Current and Future Climates.
Not available
S-EPMC7323718 | biostudies-literature
ProteomicsThe human disease gene TMEM251 is essential for lysosomal transport and viral infection
After gaining access to the endo-lysosomal pathway, several viruses depend on lysosomal cathepsin proteases to cleave their structural proteins triggering productive entry. Targeting of cathepsins and other luminal lysosomal proteins to lysosomes requires their modification with mannose 6-phosphate ...
ORGANISM(S): Homo sapiens (Human) 
2022-09-09 | PXD029746 | Pride
Glycoproteomics Mannose-6-phosphate 
UnknownPhase II-I-II study of two different doses and schedules of pralatrexate, a high-affinity substrate for the reduced folate carrier, in patients with relapsed or refractory lymphoma reveals marked activity in T-cell malignancies.
Not available
S-EPMC3651599 | biostudies-literature
ProteomicsThe Campylobacter jejuni CiaD effector co-opts the host cell protein IQGAP1 to promote cell entry
Proteomic data from pulldown performed with the recombinant Campylobacter CiaD-GST fusion was expressed in E. coli BL21(DE3) on a lysate of human cultured INT 407 cells. One non-specific binding control was performed on INT 407 cell lysates and two-pulldowns were realized with the recombinant protei...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-01-05 | MSV000086662 | MassIVE
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