O-glycoproteomics

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Biological Chemistry Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, United States (3)
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1) Department of Chemistry, Stanford University, Stanford, California, USA 2) Howard Hughes Medical Institute, Stanford, California, USA (1)
1Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Padualaan 8, 3584 CH, Utrecht, The Netherlands 2Netherlands Proteomics Center, Padualaan 8, 3584 CH, Utrecht, The Netherlands (1)
ASTRE, Univ Montpellier, CIRAD, INRA, Montpellier, France & CIRAD, UMR ASTRE, F-34398, Montpellier, France (1)
Associate Professor Glyco MS Group Copenhagen Center for Glycomics (CCG) Department of Cellular and Molecular Medicine (24.6.36) University of Copenahgen Blegdamsvej 3 2200 Copenhagen N Denmark (1)
Associate Professor Glyco MS Group Copenhagen Center for Glycomics (CCG) Department of Cellular and Molecular Medicine University of Copenahgen Blegdamsvej 3 2200 Copenhagen N Denmark (1)
Bertozzi Lab Department of Chemistry 380 Roth Way MC: 5080 Stanford CA 94305-4401 (1)
Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA (1)
Biochemistry Department, Kavli Institute for Nanoscience Discovery, University of Oxford, UK (1)
Boston University Chobanian & Avedisian School of Medicine, Department of Biochemistry and Cell Biology (1)
CNRS-IPBS Immunomodulation By Mycobacterial Lipids and Glycoconjugates 205 route de Narbonne 31077 Toulouse cedex 4 (1)
Center for Proteomics and Metabolomics Leiden University Medical Center Tel +31-71-5266394 P.J.Hensbergen@lumc.nl https://www.lumc.nl/org/proteomics-metabolomics/ https://cpm.lumc.nl (1)
Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, The Netherlands (1)
Chemistry & Biochemistry (1)
Chemistry & Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138 and Department of Microbiology, Harvard Medical School, 4 Blackfan Circle, Boston, MA 02115 (1)
College of Chemistry and Molecular Engineering, Peking University, Beijing, China (1)
College of Life Sciences, Northwest University (1)
Complex Carbohydrate Research Center, Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA. (1)
Copenhagen Center for Glycomics (CCG) Department of Cellular and Molecular Medicine University of Copenhagen (1)
Copenhagen Center for Glycomics (CCG), Department of Cellular and Molecular Medicine, University of Copenhagen, Denmark (1)
Copenhagen Center for Glycomics, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (1)
Copenhagen Center for Glycomics, Departments of Cellular and Molecular Medicine, Faculty of Health Sciences, University of Copenhagen, Blegdamsvej 3, DK-2200 Copenhagen N, Denmark (1)

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xref:PubMed:34853070 (1)

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Glyco-DIA: a method for quantitative O-glycoproteomics with in silico-boosted glycopeptide libraries

We report a LC-MS/MS O-glycoproteomics strategy using Data Independent Acquisition (DIA) mode that holds the potential for enabling direct analysis of O-glycoproteins with characterization of sites and structures of O-glycans on a proteome-wide scale with quantification of stoichiometries. To explor...

ORGANISM(S): Homo sapiens (Human)

2019-11-19 | PXD011063 | Pride

Mapping and quantification of over 2,000 O-linked glycopeptides in activated human T cells with isotope-targeted glycoproteomics

Post-translational modifications (PTMs) on proteins often function to regulate signaling cascades, with the activation of T cells during an adaptive immune response being a classic example. Mounting evidence indicates that the modification of proteins by O-linked Nacetylglucosamine (O-GlcNAc), the o...

ORGANISM(S): Homo sapiens (Human)

2018-01-25 | PXD004559 | Pride

Glycoproteomics Mass spectrometry O-glcnac T cells O-linked n-acetylglucosamine

Quantitative proteome-wide O-glycoproteomics analysis with FragPipe.

Not available

S-EPMC11648966 | biostudies-literature

Fast and comprehensive N- and O-glycoproteomics analysis with MSFragger-Glyco.

Not available

S-EPMC7606558 | biostudies-literature

Global view of domain-specific O-linked mannose glycosylation in glycoengineered cells

Protein O-linked mannose (O-Man) glycosylation is an evolutionary conserved post-translational modification, whose biosynthesis is initiated by three non-redundant enzyme families, POMT1/POMT2, TMTC1-4 and TMEM260. In this study, we applied a targeted workflow for membrane glycoproteomics to five hu...

ORGANISM(S): Homo sapiens (Human)

2024-06-10 | PXD045597 | Pride

Lc-msms O-man Glycoproteomics Ptm Glycobiology O-mannose

Targeted O-glycoproteomics for the development of diagnostic markers for advanced colorectal cancer.

Not available

S-EPMC9948623 | biostudies-literature

O-glycoproteomic datasets on the serum samples from healthy individuals

Clinical O-glycoproteomics for the development of diagnostic marker for colorectal cancer based on changes in O-glycosylation of serum protein.

ORGANISM(S): Homo Sapiens (human)

2023-07-13 | PXD035280 | JPOST Repository

O-glycoproteomic datasets on the serum samples from patients with colorectal cancer

Clinical O-glycoproteomics for the development of diagnostic marker for colorectal cancer based on changes in O-glycosylation of serum protein.