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UnknownRandomized, Prospective Evaluation Comparing Intensity of Lymphodepletion Before Adoptive Transfer of Tumor-Infiltrating Lymphocytes for Patients With Metastatic Melanoma.
Not available
S-EPMC4981979 | biostudies-literature
ProteomicsPTPN23-dependent ESCRT machinery functions as a cell death checkpoint in restraining multiple cell death pathways
In our study, a CRISPR screen of acute myeloid leukemia cells identifies protein tyrosine phosphatase non-receptor type 23 (PTPN23) as essential for survival. Loss of PTPN23 activates nuclear factor-kappa B, apoptotic, necroptotic, and pyroptotic pathways by causing the accumulation of death recepto...
ORGANISM(S): Homo Sapiens 
2024-10-15 | PXD056836 |
TranscriptomicsATF3 is a novel regulator of mouse neutrophil migration.
Expression of the activating transcription factor 3 (ATF3) gene is induced by Toll-like receptor (TLR) signaling. In turn, ATF3 protein inhibits the expression of various TLR-driven pro-inflammatory genes. Given its counter-regulatory role in diverse innate immune responses, we defined the effects o...
ORGANISM(S): Mus musculus 
2014-04-05 | E-GEOD-53973 | biostudies-arrayexpress
ProteomicsThe Campylobacter jejuni CiaD effector co-opts the host cell protein IQGAP1 to promote cell entry
Proteomic data from pulldown performed with the recombinant Campylobacter CiaD-GST fusion was expressed in E. coli BL21(DE3) on a lysate of human cultured INT 407 cells. One non-specific binding control was performed on INT 407 cell lysates and two-pulldowns were realized with the recombinant protei...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-01-05 | MSV000086662 | MassIVE
ProteomicsAged Mouse Muscle: Sedentary or Exercised Animals with or without Nicotinamide N-methyltransferase Inhibitor Treatment
Aged (22-mo) female mice (n=35), obtained from the US NIH National Institute on Aging (NIA) Aged Rodent Colony, were randomly assigned to one of four groups: saline-treated sedentary ( n=9), nicotinamide N-methyltransferase inhibitor (NNMTi)-treated sedentary (10 mg/kg body weight; n=9), saline-trea...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2024-05-07 | MSV000094700 | MassIVE
ProteomicsThe modified RNA base acp3U is an attachment site for N-glycans in glycoRNA
GlycoRNA consists of RNAs modified with secretory N-glycans that are presented on the cell surface. While previous work supported a covalent linkage between RNA and glycans, the direct chemical nature of the RNA-glycan connection was not described. Here we develop a sensitive and scalable protocol t...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-10-31 | MSV000093213 | MassIVE
GenomicsGenome Wide Association for Asthma and Lung Function

The SNP Typing for Association with Multiple Phenotypes from Existing Epidemiologic (STAMPEED) asthma project includes subjects with asthma and controls from the Chicago Asthma Genetics Study (CAG), NHLBI multicenter Severe Asthma Research Program (SARP) and NHLBI Collaborative Studies ...

phs000355.v1.p1 | EGA
Genomicsena-DATASET-DAVELAB-22-03-2017-21:30:50:663-38 - samples
Whole exome sequencing of hepatosplenic T cell lymphoma (HSTL) tumors, paired normals, and cell lines, including (1) 68 exome capture, paired-end Illumina Hiseq sequencing, BAM files from HSTL tumor samples, (2) 20 exome capture, paired-end Illumina Hiseq sequencing, BAM files from HSTL paired norma...
EGAD00001003246 | EGA
GenomicsGenetic Basis of Hepatosplenic T Cell Lymphoma (HSTL)
Hepatosplenic T cell lymphoma (HSTL) is a rare and lethal lymphoma; the genetic drivers of this disease are unknown.  Through whole exome sequencing of 68 HSTLs, we define recurrently mutated driver genes and copy number alterations in the disease. Chromatin modifying genes including SETD2, INO80 an...
EGAS00001002182 | EGA
GenomicsDAC for Dave Lab, Duke University
Data Access Committee EGAC00001000538
EGAC00001000538 | EGA
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