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ProteomicsRadioproteomics stratifies molecular response to antifibrotic treatment in pulmonary fibrosis
Antifibrotic therapy with nintedanib is the clinical mainstay in the treatment of progressive fibrosing interstitial lung disease (ILD). High-dimensional medical image analysis, known as radiomics, provides quantitative insights into organ-scale pathophysiology, generating digital disease fingerprin...
ORGANISM(S): Mus musculus (Mouse) 
2024-10-17 | PXD052594 | Pride
Interstitial lung disease Radiomics Proteomics Multiomics Imaging Lung fibrosis Nintedanib 
TranscriptomicsGenome-wide studies of histone Me2 SWIRM and polyamine oxidase domain homologues of mammalian LSD1
In order to gain a more global view of the activity of histone demethylases we report here studies of the two fission yeast SWIRM and polyamine oxidase domain homologues of mammalian LSD1. Consistent with previous work (Nicolas et al., 2006) we find that the two S. pombe proteins, which we name Swm...
ORGANISM(S): Schizosaccharomyces pombe 
2010-05-27 | E-GEOD-6224 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of the WalKR regulon in Staphylococcus aureus
The WalKR regulon was studied by comparing genes expression in a strain producing a constitutively active WalR regulator (WalRc) versus the wild type strain carrying the empty expression vector. Hybridizations were performed with three independent biological replicates. Our data allowed to identify ...
ORGANISM(S): Staphylococcus aureus 
2012-09-13 | E-GEOD-29337 | biostudies-arrayexpress
UnknownMultimodal brain age estimates relate to Alzheimer disease biomarkers and cognition in early stages: a cross-sectional observational study.
Not available
S-EPMC9988262 | biostudies-literature
TranscriptomicsChromatin immunoprecipitation of mouse hematopoietic cell lines and tissue-types to identify histone modification and transcription factor binding sites
Histone modification and transcription factor ChIP-chip in hematopoietic cell lines and tissue-types
ORGANISM(S): Mus musculus 
2009-01-28 | E-TABM-431 | biostudies-arrayexpress
GenomicsThe Transcriptional Programme Controlled by Scl/Tal1 Gene during Early Embryonic Haematopoietic Development
The basic-helix-loop-helix transcription factor Scl/Tal1 controls the development and subsequent differentiation of haematopoietic stem cells (HSCs). However, since few Scl target genes have been validated to date, the underlying mechanisms have remained largely unknown. Here we have employed ChIP...
ORGANISM(S): Mus musculus 
2009-06-19 | E-GEOD-15806 | biostudies-arrayexpress
UnknownClinical, Radiologic, Pathologic, and Molecular Characteristics of Long-Term Survivors of Diffuse Intrinsic Pontine Glioma (DIPG): A Collaborative Report From the International and European Society for Pediatric Oncology DIPG Registries.
Not available
S-EPMC6075859 | biostudies-literature
ModelsChaouiya2013 - EGF and TNFalpha mediated signalling pathway
Chaouiya2013 - EGF and TNFalpha mediated signalling pathway This model is described in the article: SBML qualitative models: a model representation format and infrastructure to foster interactions between qualitative modelling formalisms and tools. Chaouiya C, Bérenguier D...
2024-09-02 | BIOMD0000000562 | BioModels
Genomicsena-DATASET-MUGQIC-22-03-2014-14:08:20:709-444 - samples
Whole exome sequencing of paediatric glioblastoma with mutations reported in the manuscript: Mutations in ACVR1, FGFR1 and TP53 associate with tumor location in histone H3 K27M pediatric midline high-grade astrocytoma
EGAD00001000792 | EGA
TranscriptomicsRNA-Seq on Illumina platform of Drosophila DrosDel deficiency lines
RNA-Seq reads of DrosDel deficiency (Df/+) and parental strain diploid flies along with spike-in controls was performed on the Illumina platform. Samples are named in this dataset according to the following sample naming scheme: tissue_genotype shorthand_sex_biological replicate #_platform. We seque...
ORGANISM(S): Drosophila melanogaster 
2012-04-03 | E-GEOD-31549 | biostudies-arrayexpress
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