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Autophagy is a highly conserved lysosomal degrative pathway important for maintaining cellular homeostasis. Much of our current knowledge of autophagy is focused on the initiation steps with the later steps, particularly lysosomal fusion leading to autolysosome formation and the subsequent role of l...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2022-02-15 | PXD016675 | Pride
We discovered that platelets become activated by platelet factor 4 and have looked into how this is the case. We used phosphoproteomics to identify proteins that were phosphorylated in a band on a Western blot at 95 kDa and identified phospho STAT5. We have subsequently shown that PF4 activates plat...
ORGANISM(S): Homo sapiens (Human) 
2024-06-16 | PXD043558 | Pride
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