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ProteomicsHigh-throughput discovery of Chagas Disease antigens and their linear B-cell epitopes using high-density peptide arrays
Screening of antibody-binding specificities from pooled normal (healthy) and chronic Chagas Disease patients.
ORGANISM(S): Homo sapiens 
2015-06-24 | E-MTAB-3008 | biostudies-arrayexpress
TranscriptomicsInvestigation of gene expression in biopsies from psoriasis patients before and after adalimumab treatment. Paired biopsies from non-lesional and lesional before treatment start and from psoriatic skin four and 14 days treatment start were included.
Gene expression in psoriatic skin has not previously been described as early as four days after treatment start. No clinical or histological changes are seen four days after treatment start but few genes have been shown to be regulated that early. We aimed to investigate changes in gene expression i...
ORGANISM(S): Homo sapiens 
2016-11-21 | E-MTAB-5262 | biostudies-arrayexpress
Proteomics,MultiomicsmiR-625-3p regulates oxaliplatin resistance by targeting MAP2K6-p38 signaling in human colorectal adenocarcinoma cells
Oxaliplatin (oxPt) resistance in colorectal cancers (CRC) is a major unsolved problem. Consequently, predictive markers and a better understanding of resistance mechanisms are urgently needed. To investigate if the recently identified predictive miR-625-3p is functionally involved in oxPt resistance...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080762 | MassIVE
Genomicsena-DATASET-AUH-06-07-2017-00:05:45:851-367 - samples
RNAseq data from the study: "Widespread DNA hypomethylation and differential gene expression in Turner syndrome".
EGAD00001003428 | EGA
GenomicsArray_dataset_Female
DNAm Case samples using Illumina Infinium 450K
EGAD00010001262 | EGA
GenomicsArray_dataset_TS
DNAm Case samples using Illumina Infinium 450K
EGAD00010001261 | EGA
GenomicsArray_dataset_Male
DNAm Case samples using Illumina Infinium 450K
EGAD00010001260 | EGA
GenomicsWidespread DNA hypomethylation and differential gene expression in Turner syndrome
Adults with 45,X monosomy (Turner syndrome) reflect a surviving minority since more than 99% of fetuses with 45,X monosomy die in utero. In adulthood 45,X monosomy is associated with increased morbidity and mortality, although strikingly heterogeneous with some individuals left untouched while other...
EGAS00001002190 | EGA
ProteomicsHeLa proteome of 12,250 protein-coding genes
We developed an optimized multi-shot proteomics workflow based on high-resolution offline high pH reversed-phase peptide separation of high peptide loads collecting many fractions that were in turn analyzed by short online chromatographic separations and fast peptide sequencing using orbitrap tandem...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000081563 | MassIVE
TranscriptomicsNon-coding RNA expression in colorectal cancer
Expression was measured in 113 colorectal cancer samples using a costumized array. Expression was measured in 113 human colorectal cancer samples using a custom-designed array containing 26,910 non-coding RNA features and a set of 6,856 protein-coding genes.
ORGANISM(S): Homo sapiens 
2016-01-12 | E-GEOD-76713 | biostudies-arrayexpress
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