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TranscriptomicsMicroRNA identity and abundance in porcine skeletal muscles determined by deep sequencing
MicroRNAs (miRNA) are short single-stranded RNA molecules that regulate gene expression post-transcriptionally by binding to complementary sequences in the 3' untranslated region (3' UTR) of target mRNAs. MiRNAs participate in the regulation of myogenesis, and identification of the complete set of m...
ORGANISM(S): Sus scrofa 
2009-11-24 | E-GEOD-14584 | biostudies-arrayexpress
MetabolomicsTissue, urine and serum NMR metabolomics dataset from a 5/6 nephrectomy rat model of chronic kidney disease

Serum, urine and tissue from a rat model of chronic kidney disease (CKD) were analysed using nuclear magnetic resonance (NMR) spectroscopy-based metabolomics methods, and compared with samples from sham operated rats. Both urine and serum were sampled at multiple timepoints, and the results have ...

2020-11-16 | MTBLS2052 | MetaboLights
GenomicsGenome-Wide Profiling of Peroxisome Proliferator-Activated Receptor M-NM-3 in Primary Epididymal, Inguinal, and Brown Adipocytes Reveals Depot-Selective Binding Correlated with Gene Expression
Here we have employed chromatin immunoprecipitation combined with deep sequencing to map and compare PPARM-NM-3 binding in in vitro differentiated primary mouse adipocytes isolated from epididymal, inguinal, and brown adipose tissues. While these PPARM-NM-3 binding profiles are overall similar, the...
ORGANISM(S): Mus musculus 
2012-10-11 | E-GEOD-41481 | biostudies-arrayexpress
UnknownDirect isolation of poly(A)+ RNA from 4 M guanidine thiocyanate-lysed cell extracts using locked nucleic acid-oligo(T) capture.
Not available
S-EPMC407836 | biostudies-literature
TranscriptomicsTranscription factor cooperativity in early adipogenic hotspots and super-enhancers
Here we have used a combination of advanced proteomics and genomics approaches to investigate the extent and mechanisms of transcription factor cross-talk at genomic hotspots. We identify ~12,000 transcription factor hotspots in the early phase of adipogenesis, and we find evidence of both simultane...
ORGANISM(S): Mus musculus 
2014-04-17 | E-GEOD-56872 | biostudies-arrayexpress
UnknownCharacterization of the elastic properties of the nuclear envelope.
Not available
S-EPMC1578255 | biostudies-literature
UnknownPrognostic Significance of Sentinel Lymph Node Status in Thick Primary Melanomas (> 4 mm).
Not available
S-EPMC10625939 | biostudies-literature
MetabolomicsSystem-wide analysis of short-term response to high temperature in Pinus radiata

Pinus radiata seedlings, the most widely planted pine species in the world, were exposed to temperatures within a range mimicking future scenarios based on current models of heat increase. The short-term heat response in P. radiata was studied in detail by exploring the metabolo...

2023-08-14 | MTBLS4567 | MetaboLights
ProteomicsNew mode of methanogenesis observed in the coal degrading methanogen Methermicoccus shengliensis
Methane-generating Archaea drive the final step in anaerobic organic compound mineralization and dictate the carbon flow of Earth’s diverse anaerobic ecosystems. Although such Archaea were presumed to be restricted to life on simple compounds like H2, acetate or methanol, an archaeon, Methermicoccus...
ORGANISM(S): Methermicoccus shengliensis DSM 18856 
2021-06-20 | PXD018934 | Pride
Demethoxylation Methyl transfer Methanogen Methoxylated aromatic compounds 
UnknownFragment-Based Screening Identifies Novel Non-Amino Acid Inhibitors of the Sodium-Coupled Neutral Amino Acid Transporter SNAT2.
Not available
S-EPMC12405023 | biostudies-literature
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