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TranscriptomicsMetabolic switching in Streptomyces coelicolor wild type, time series under glutamate depletion condition
During the lifetime of a fermenter culture, the soil bacterium S. coelicolor undergoes a major metabolic switch from exponential growth to antibiotic production. We have studied gene expression patterns during this switch, using a specifically designed Affymetrix GeneChip and a high-resolution time-...
ORGANISM(S): Streptomyces coelicolor 
2011-12-31 | E-GEOD-30569 | biostudies-arrayexpress
TranscriptomicsThe PII protein GlnK is a pleiotropic regulator for morphological differentiation and secondary metabolism in Streptomyces coelicolor
This SuperSeries is composed of the following subset Series: GSE30569: Metabolic switching in Streptomyces coelicolor wild type, time series under glutamate depletion condition GSE30570: Metabolic switching in Streptomyces coelicolor time series under glutamate depletion of mutant SCglnK-3. Refer to...
ORGANISM(S): Streptomyces coelicolor 
2011-12-31 | E-GEOD-30571 | biostudies-arrayexpress
UnknownImproving taxonomic classification with feature space balancing.
Not available
S-EPMC10415173 | biostudies-literature
TranscriptomicsDifferential RNA-seq (dRNA-seq) for annotation of transcriptional start sites and small RNAs in Helicobacter pylori
In this study transcriptional start sites (TSS) for H. pylori 26695 were determined To detect the complement of transcripts expressed from H. pylori, we collected three independent biological replicates (B1 – B3) from 26695 wild type strain grown to mid-exponential (OD 600 ~0.6) phase under microaer...
ORGANISM(S): Helicobacter pylori 26695 
2015-07-01 | E-GEOD-67564 | biostudies-arrayexpress
TranscriptomicsMetabolic switches and adaptations deduced from the proteomes of Streptomyces coelicolor wild type and phoP mutant grown in batch culture
Bacteria in the genus Streptomyces are soil dwelling oligotrophs and important producers of secondary metabolites. Previously we showed that global mRNA expression was subject to a series of metabolic and regulatory switches during the life time of a fermentor batch culture of S. coelicolor M145. He...
ORGANISM(S): Streptomyces coelicolor 
2011-12-31 | E-GEOD-31068 | biostudies-arrayexpress
TranscriptomicsMetabolic switching of the PII protein GlnK in Streptomyces coelicolor
GlnK is an important nitrogen sensor protein in Streptomyces coelicolor. Deletion of glnK results in a medium-dependent failure of aerial mycelium and spore formation and loss of antibiotic production. Thus, GlnK is not only a regulator of nitrogen metabolism but also of morphological differentiatio...
ORGANISM(S): Streptomyces coelicolor 
2011-12-31 | E-GEOD-30570 | biostudies-arrayexpress
TranscriptomicsIdentification and validation of antisense RNAs in Escherichia coli
In this study transcriptional start sites (TSS) of E. coli were determined for several growth conditions To detect the complement of transcripts expressed from E. coli, we collected two independent biological replicates (B1 and B2 samples) from MG1655 wild type strain grown to exponential (OD 600 ~0...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2014-10-18 | E-GEOD-55199 | biostudies-arrayexpress
TranscriptomicsRNA-Sequenzing of Streptomyces coelicolor A3(2) (M1152) in timeseries
SYSTERACT: Systematic Rebuilding of Actinomycetes for Natural Product Formation For several decades antibiotics have saved millions of lives, but their overuse makes them less effective due to increase in bacterial resistance. Because of this major clinical and public health problem, there is an urg...
ORGANISM(S): Streptomyces coelicolor A3(2) 
2019-10-09 | GSE132488 | GEO
TranscriptomicsRNA-Sequencing of Streptomyces coelicolor A3(2) (M145) in timeseries
SYSTERACT: Systematic Rebuilding of Actinomycetes for Natural Product Formation For several decades antibiotics have saved millions of lives, but their overuse makes them less effective due to increase in bacterial resistance. Because of this major clinical and public health problem, there is an urg...
ORGANISM(S): Streptomyces coelicolor A3(2) 
2019-10-09 | GSE132487 | GEO
UnknownOpen reading frames provide a rich pool of potential natural antisense transcripts in fungal genomes.
Not available
S-EPMC1201330 | biostudies-literature
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