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ProteomicsMapping the human chondroitin sulfate glycoproteome reveals an unexpected correlation between glycan sulfation and attachment site characteristics
Chondroitin sulfate proteoglycans (CSPGs), an important class of carbohydrate-modified proteins, are composed of chondroitin sulfate (CS) polysaccharide(s) attached to different core proteins. CS polysaccharides interact with a multitude of protein ligands to control key events in homeostasis and de...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD037990 | Pride
Glycosaminoglycans  proteoglycans  glycoproteomics  glycopeptides 
TranscriptomicsConcomitant deletions of tumor suppressor genes MEN1 and AIP are essential for the pathogenesis of the brown fat tumor hibernoma
Hibernomas are benign tumors with morphological features resembling brown fat. They consistently display cytogenetic rearrangements, typically translocations, involving chromosome band 11q13. Here we demonstrate that these aberrations are associated with concomitant deletions of AIP and MEN1, tumor ...
ORGANISM(S): Homo sapiens 
2010-11-24 | E-GEOD-19040 | biostudies-arrayexpress
ProteomicsMdpS and MdpS2 structurally and functionally diverge to regulate Streptococcus oralis mucin degradation
The human oral cavity harbors a diverse microbial community, with oral streptococci, particularly the Streptococcus mitis group, playing a pivotal role in biofilm formation and oral health. Among these, Streptococcus oralis is a key early colonizer that stabilizes oral biofilms. Here, we identify tw...
ORGANISM(S): Homo sapiens (Human) 
2025-11-10 | PXD062603 | Pride
Muc5b Streptococcus oralis Biofilm dynamics Mucin degrading proteases Oral microbiome Mucin degradation 
ProteomicsLC-MS/MS analysis of I?I proteoglycopeptides
The inter-alpha-trypsin inhibitor (I?I) complex is a macromolecular arrangement of structurally related heavy chain proteins covalently cross-linked to the chondroitin sulfate (CS) chain of the proteoglycan bikunin. The I?I complex is abundant in plasma and associated with inflammation, kidney disea...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080725 | MassIVE
ModelsUhlén2015 - Human tissue-based proteome metabolic network - lymph node
Uhlén2015 - Human tissue-based proteome metabolic network - lymph node Human lymph node specific proteome metabolic network This model is described in the article: Tissue-based map of the human proteome Uhlén M, Fagerberg L, Hallström BM, Lindskog C, Oksvold P, Mardinogl...
2015-01-28 | MODEL1411240016 | BioModels
ModelsUhlén2015 - Human tissue-based proteome metabolic network - stomach
Uhlén2015 - Human tissue-based proteome metabolic network - stomach Human stomach specific proteome metabolic network This model is described in the article: Tissue-based map of the human proteome Uhlén M, Fagerberg L, Hallström BM, Lindskog C, Oksvold P, Mardinoglu A, S...
2015-01-28 | MODEL1411240017 | BioModels
ModelsUhlén2015 - Human tissue-based proteome metabolic network - adipose
Uhlén2015 - Human tissue-based proteome metabolic network - adipose Human adipose tissue specific proteome metabolic network This model is described in the article: Tissue-based map of the human proteome Uhlén M, Fagerberg L, Hallström BM, Lindskog C, Oksvold P, Mardinog...
2015-01-28 | MODEL1411240001 | BioModels
ModelsUhlén2015 - Human tissue-based proteome metabolic network - bone marrow
Uhlén2015 - Human tissue-based proteome metabolic network - bone marrow Human bone marrow tissue specific proteome metabolic network This model is described in the article: Tissue-based map of the human proteome Uhlén M, Fagerberg L, Hallström BM, Lindskog C, Oksvold P, ...
2015-01-28 | MODEL1411240003 | BioModels
ModelsUhlén2015 - Human tissue-based proteome metabolic network - adrenal
Uhlén2015 - Human tissue-based proteome metabolic network - adrenal Human adrenal specific proteome metabolic network This model is described in the article: Tissue-based map of the human proteome Uhlén M, Fagerberg L, Hallström BM, Lindskog C, Oksvold P, Mardinoglu A, S...
2015-01-28 | MODEL1411240002 | BioModels
ModelsUhlén2015 - Human tissue-based proteome metabolic network - testis
Uhlén2015 - Human tissue-based proteome metabolic network - testis Human testis specific proteome metabolic network This model is described in the article: Tissue-based map of the human proteome Uhlén M, Fagerberg L, Hallström BM, Lindskog C, Oksvold P, Mardinoglu A, Siv...
2015-01-28 | MODEL1411240018 | BioModels
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