Glycosaminoglycans

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1 Department of Anaesthesiology, LMU University Hospital, Ludwig-Maximilian-University (LMU), Munich, Germany 2 Walter Brendel Center of Experimental Medicine, Research Unit Immune Function and Immune Metabolism, Ludwig-Maximilian-University (LMU), Munich, Germany (1)
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Chiara Guerrera, IRHC, HDR Head of the Necker Proteomics Faculty of Medecine, University Paris Cité SFR Necker INSERM US24 160 rue de Vaugirard | 75015 Paris Tél. 01 40 61 54 6 (1)
Copenhagen Center for Glycomics, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark. (1)
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Department of Clinical Chemistry and Transfusion Medicine, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden (1)
Department of Infectious Diseases, Immunology and Sexual Health and Department of Medicine, St George Hospital, University of New South Wales, 2 South Street, Kogarah, Sydney, NSW 2217, Australia (1)
Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. (1)
Department of Medical Sciences, Institute of Biomedicine (iBiMED), University of Aveiro, 3810-193 Aveiro, Portugal. (1)
Department of Molecular Systems Biology, Helmholtz Centre for Environmental Research – UFZ, Leipzig, Germany (1)
Department of Orthopaedic Surgery, Duke University School of Medicine, Durham, North Carolina, United States of America (1)
Dept. of Biochemistry, Center for Biomedical Mass Spectrometry, Boston University 2Bioinformatics Program, Boston Universty (1)
Director Glycoscience Center of Research Excellence (GlyCORE) Associate Professor of Pharmacology Associate Professor of Chemistry and Biochemistry The University of Mississippi School of Pharmacy Department of BioMolecular Sciences P.O. Box 1848 445 Faser Hall University, MS 38677-1848 (1)
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Lachlan J. Smith, Ph.D. Associate Professor Department of Orthopaedic Surgery Perelman School of Medicine University of Pennsylvania 371 Stemmler Hall, 3450 Hamilton Walk Philadelphia, PA, 19104 USA (1)
Macquarie University, Department of Molecular Science (1)
Medical Biochemistry and Biophysics, karolinska Institutet, Stockholm, Sweden (1)

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LC-MS/MS characterization of xyloside-primed glycosaminoglycans with cell-specific cytotoxic properties reveals structural diversity and novel glycan modifications

Structural characterization of glycosaminoglycans remains a challenge and is essential for determining not only structure-function relationships between glycosaminoglycans and the biomolecules with which they interact, but also to gain insight into the biosynthesis of glycosaminoglycans. We have rec...

ORGANISM(S): Homo sapiens (Human)

2018-05-07 | PXD009652 | Pride

Glycosaminoglycans and Proteoglycans.

Not available

S-EPMC5874723 | biostudies-literature

Quantitative proteomics in osteoblasts-released matrix vesicles

The use of glycosaminoglycan-coated implants are a promising therapeutic approach in bone research since they mimic the native bone environment and facilitate the skeletonegenesis. Previous studies showed that sulfated glycosaminoglycans induce the osteoblastic phenotype, but the overall effect on t...

ORGANISM(S): Homo sapiens (Human)

2015-11-30 | PXD002498 | Pride

Human Lc-msms Exosome Glycosaminoglycans Osteoblasts Silac Matrix vesicles

Nutrient niche specificity for glycosaminoglycans

PRJNA837438 | ENA

Cysteine cathepsin activity regulation by glycosaminoglycans.

Not available

S-EPMC4283429 | biostudies-literature

To better understand the molecular basis for modulation of glycosaminoglycans (GAGs) and proteoglycans post-UV exposure

UV irradiation is a major environmental effector of skin damage and aging. Elevated levels of glycosaminoglycans (GAGs), as measured by Hale’s stain, are seen following cutaneous photodamage. Preliminary data from our lab indicates that this is a complex response involving differential regulation of...

ORGANISM(S): Homo sapiens

2011-10-03 | GSE32552 | GEO

Microarray analysis of Normal and MPS VII mouse aorta

Mucopolysaccharidosis VII (MPS VII) is due to mutations within the gene encoding the lysosomal enzyme beta-glucuronidase, and results in the accumulation of glycosaminoglycans. MPS VII causes aortic dilatation and elastin fragmentation. In this study we performed microarray analysis of ascending ao...

ORGANISM(S): Mus musculus

2011-10-09 | E-GEOD-30657 | biostudies-arrayexpress

Proteoglycans and their heterogeneous glycosaminoglycans at the atomic scale.

Not available

S-EPMC4356732 | biostudies-literature

Glycosaminoglycans activate peptidylarginine deiminase 4 by enhancing calcium affinity.

Not available

S-EPMC12595441 | biostudies-literature

Utilization of Glycosaminoglycans/Proteoglycans as Carriers for Targeted Therapy Delivery.

Not available

S-EPMC4581573 | biostudies-literature

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