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ProteomicsThe glycosaminoglycan-dependent interactome of neurexin-1 in human fetal glial cells
Neurexins are synaptic adhesion molecules best characterized in neurons, where they regulate synapse assembly and function, with emerging evidence indicating they are also abundantly expressed by astrocytes. To elucidate the interactome of NRXN1α, we employed a proximity labeling strategy in culture...
ORGANISM(S): Homo sapiens (Human) 
2025-12-22 | PXD069099 | Pride
Proximity tagging Glycosaminoglycan Interactome Thrombospondin-1 Neurexin-1 
ProteomicsGlycosaminoglycan linkage region of urinary bikunin as a potentially useful biomarker for β3GalT6-deficient spondylodysplastic Ehlers-Danlos syndrome
The spondylodysplastic type of Ehlers-Danlos syndromes (spEDS) is caused by genetic defects in the B4GALT7 or B3GALT6 genes both deranging the biosynthesis of the glycosaminoglycan linkage region of chondroitin/dermatan sulfate and heparan sulfate proteoglycans. In this study we have analyzed the li...
ORGANISM(S): Homo sapiens (Human) 
2022-06-29 | PXD033230 | Pride
Liquid chromatography Ehlers-danlos syndrome Tandem mass spectrometry Glycoproteomics Linkeropathies Β3galt6 Glycopeptides Bikunin Glycosaminoglycan linkage region 
ProteomicsArylsulfatase L (ARSL) Controls Glycosaminoglycan Sulfation During Skeletal Development
Proteoglycans are essential components of the cartilage extracellular matrix (ECM), with glycosaminoglycan (GAG) chains playing a crucial role in skeletal development. This study identifies a previously unknown substrate of arylsulfatase L (ARSL) a Golgi-localized enzyme. To investigate ARSL’s physi...
ORGANISM(S): Rattus norvegicus (Rat) 
2026-06-15 | PXD061172 | Pride
Arsl Skeletal Glycosaminoglycan 
ProteomicsSpatial evaluation of transcriptomic and proteomic data in ALK rearranged lung cancer - a pilot study
Spatial evaluation of transcriptomic and proteomic data in ALK rearranged lung cancer - a pilot study
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-04-20 | MSV000089286 | MassIVE
GenomicsGlycosaminoglycan-driven lipoprotein uptake protects tumours from ferroptosis
Glycosaminoglycan-driven lipoprotein uptake protects tumours from ferroptosis
PRJNA1258287 | ENA
TranscriptomicsTranscription profiling of human fibroblasts grown in petri dishes vs. attached to a tissue engineering scaffold sampled at 7 timepoints.
A goal of tissue engineering is to produce a scaffold material that will guide cells to differentiate and regenerate functional replacement tissue at the site of injury. Little is known about how cells respond on a molecular level to tissue engineering scaffold materials. In this work we used oligon...
ORGANISM(S): Homo sapiens 
2007-10-26 | E-GEOD-6432 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human fibroblasts grown on TCPS plates, Collagen-GAG 2 D plate and Collagen-GAG 3D mesh
All mRNA was isolated after 8 hours of culture time in each of three culture conditions. (1) TCPS Plate, (2) Collagen-GAG 2 dimensional coated plate and (3) collagen-GAG three dimensional mesh.
ORGANISM(S): Homo sapiens 
2008-06-11 | E-GEOD-1937 | biostudies-arrayexpress
UnknownChemogenesis of an antiangiogenic glycosaminoglycan.
Not available
S-EPMC4060934 | biostudies-literature
UnknownHost glycosaminoglycan confers susceptibility to bacterial infection in Drosophila melanogaster.
Not available
S-EPMC2632041 | biostudies-literature
ProteomicsPhenotyping CHST3-related skeletal dysplasia using freezer-induced patient urine sediments
Using freezer-induced urine sediments, we show that we can perform regular proteomics after glycosaminoglycan digests and proteome digestion on PVDF membrane.
ORGANISM(S): Homo sapiens (Human) 
2023-10-10 | PXD039081 | Pride
Skeletal dysplasia Glycosaminoglycans Freezer-induced urine sediments 
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